Structural insights into SARS-CoV-2 proteins

R Arya, S Kumari, B Pandey, H Mistry, SC Bihani… - Journal of molecular …, 2021 - Elsevier
… these structures to atomic details provided important insights … of these structures are also
useful as a target for the structure-… the available structural information on SARS-CoV-2 proteins. …

SARSCoV‐2, the pandemic coronavirus: Molecular and structural insights

SB Kadam, GS Sukhramani, P Bishnoi… - Journal of basic …, 2021 - Wiley Online Library
… the molecular aspects of SARS-CoV-2 including secondary structures in the genome and …
spread of the SARS-CoV-2. The mutations and the haplotypes reported in the SARS-CoV-2 …

Evolutionary and structural insights about potential SARS-CoV-2 evasion of nirmatrelvir

KS Yang, SZ Leeuwon, S Xu… - Journal of medicinal …, 2022 - ACS Publications
The US FDA approval of PAXLOVID, a combination therapy of nirmatrelvir and ritonavir has
significantly boosted our morale in fighting the COVID-19 pandemic. Nirmatrelvir is an …

[HTML][HTML] Insights into SARS-CoV-2 genome, structure, evolution, pathogenesis and therapies: Structural genomics approach

AAT Naqvi, K Fatima, T Mohammad, U Fatima… - … et Biophysica Acta (BBA …, 2020 - Elsevier
… Further, this analysis provides a brief insight into the non-structural proteome as well …
SARS-CoV-2 polyprotein that may be useful to understand the structural basis of infection, structure-…

Structural insights into SARS coronavirus proteins

M Bartlam, H Yang, Z Rao - Current opinion in structural biology, 2005 - Elsevier
… of a global outbreak of SARS (severe acute respiratory … structural proteins, sixteen non-structural
proteins and eight accessory proteins. The availability of structures of SARS coronavirus

Structural insight into the role of novel SARS-CoV-2 E protein: A potential target for vaccine development and other therapeutic strategies

M Sarkar, S Saha - PloS one, 2020 - journals.plos.org
… Thus, this study gives a structural insight into the putative mechanism of action of the
novel SARS-CoV-2 E protein as a conformation-dependent ion channel conducting H + ions. …

Biochemical and structural insights into SARS-CoV-2 polyprotein processing by Mpro

R Yadav, VV Courouble, SK Dey, JJEK Harrison… - Science …, 2022 - science.org
structural insights into CoV-2 polyproteins, which will help us in understanding the structure-…
, drug design, and the fundamental biology of polyprotein activity and processing in CoV-2. …

Structural insights into the cross-neutralization of SARS-CoV and SARS-CoV-2 by the human monoclonal antibody 47D11

J Fedry, DL Hurdiss, C Wang, W Li, G Obal, I Drulyte… - Science …, 2021 - science.org
The emergence of SARS-CoV-2 … SARS-CoV-2 and SARS-CoV and protecting against the
associated respiratory disease in an animal model. Here, we report cryo-EM structures of both …

Structural insights into the SARS-CoV-2 Omicron RBD-ACE2 interaction

J Lan, X He, Y Ren, Z Wang, H Zhou, S Fan, C Zhu… - Cell research, 2022 - nature.com
Dear Editor, The global fight against the COVID-19 pandemic is still in great uncertainty due
to the emergence of SARS-CoV-2 variants, especially the variants of concern (VOCs) with …

Structural insights into coronavirus entry

MA Tortorici, D Veesler - Advances in virus research, 2019 - Elsevier
SARS-CoV and MERS-CoV are zoonotic viruses that crossed the species barrier using
bats/palm civets and dromedary camels, respectively. No specific treatments or vaccines have …