Effect of Huangqin decoction on regulating intestinal flora in colitis mice characterized as inhibition of the NOD2-dependent pathway

S Huang, J He, Y Chen, X Wang, Y Li, Y Su… - Pharmaceutical …, 2022 - Taylor & Francis
… with NOD2) and their downstream signalling pathways to release inflammatory cytokines, …
-dependent pathway is found to be influential among multiple inflammatory signalling pathways

San Wu Huangqin decoction regulates inflammation and immune dysfunction induced by influenza virus by regulating the NF-κB signaling pathway in H1N1-infected …

Q Ma, M Ren, J Luo - Journal of ethnopharmacology, 2021 - Elsevier
signal pathway was selected to study the antiviral effect of SWHD in this experiment. Results
showed that the IKK/IκB/NF-κB pathway … IKK/IκB/NF-κB signal pathway. This study provides …

Effect of Huangqin Decoction on NF-κB/NLRP3/Caspase-1 Signaling Pathway and Pyroptosis in Kidney of Diabetic Nephropathy Rats

J LIU, B YAN, J ZHANG, Y MA, Z TIAN… - China …, 2022 - manu60.magtech.com.cn
Huangqin DecoctionHuangqin Decoction exerts a definite effect on DN rats, at least partly,
through inhibition of the NF-κB/NLRP3/Caspase-1-dependent pyroptosis signaling pathway

Prevention of ulcerative colitis by Huangqin decoction: reducing the intestinal epithelial cell apoptosis rate through the IFN-γ/JAK/ETS signalling pathway

X Mo, K Tang, L Deng, X Zhou, X Li, Y Zhang… - Pharmaceutical …, 2022 - Taylor & Francis
… The traditional Chinese medicine compound preparation Huangqin decoction (HQD) has
been widely used in the clinical treatment of UC, but the specific mechanism of its function is …

[PDF][PDF] A network pharmacology approach to investigate the mechanisms of Huangqin decoction in the treatment of irinotecan-induced gastrointestinal toxicity

Y Wang, Q Xu, ZQ Feng - Asian Toxicology Research, 2020 - tmrjournals.cn
… of Huangqin decoction play an important role in the treatment of irinotecan-related gastrointestinal
toxicity through multi-target and multi-pathway… In order to detect the signal pathways of …

[HTML][HTML] Anti-inflammatory effects of Huangqin decoction on dextran sulfate sodium-induced ulcerative colitis in mice through regulation of the gut microbiota and …

M Li, H Luo, X Wu, Y Liu, Y Gan, N Xu… - Frontiers in …, 2020 - frontiersin.org
… Graphical Abstract This study demonstrated that supplementation of Huangqin decoction
(HQD) … the gut microbiota and suppressing Ras-PI3K-Akt-HIF-1α and NF-κB pathways in mice. …

Effects of Huangqin Decoction on ulcerative colitis by targeting estrogen receptor alpha and ameliorating endothelial dysfunction based on system pharmacology

M Li, M Li, N Xu, Z Li, Y Zhang, Y Gan, H Luo… - Journal of …, 2021 - Elsevier
… Based on clinical studies, the estrogen signaling pathway may play key roles in IBD and
the high expression of ERs may suppress inflammatory pathways (Shao et al., 2020), which is …

[HTML][HTML] Integrated bioinformatics and network pharmacology to identify the therapeutic target and molecular mechanisms of Huangqin decoction on ulcerative Colitis

Y Wu, X Liu, G Li - Scientific reports, 2022 - nature.com
… Enrichment analysis showed that HQD played a role in TNF signaling pathway, IL-17
signaling pathway, Th17 cell differentiation, etc. IL6, TNF, IL1B, PTGS2, ESR1, and PPARG with …

[HTML][HTML] Huangqin decoction alleviates lipid metabolism disorders and insulin resistance in nonalcoholic fatty liver disease by triggering Sirt1/NF-κB pathway

BF Yan, LF Pan, YF Quan, Q Sha… - World Journal of …, 2023 - ncbi.nlm.nih.gov
… of Huangqin decoction and structures of the major phytochemicals in Huangqin decoction.
A and B: High-performance liquid chromatography profiles of Huangqin decoction (HQD) and …

[Retracted] Integrated Network Pharmacology and Gut Microbiota Study on the Mechanism of Huangqin Decoction in Treatment Diabetic Enteritis

X Xu, C Fang, F Lu, S Liu - Applied Bionics and Biomechanics, 2022 - Wiley Online Library
Pathways in Microbiota Sample Communities In order to identify the signaling pathway of
Huangqin decoction … 170 signaling pathways through enrichment, as shown in Table 3 below. …