… deployed as combination therapies to improve therapeutic efficacy and … malaria, is still
administered frequently. However, this model focuses on the treatment of uncomplicated malaria …

… new antimalarial leads through in silico modeling. In the future, the potential leads can be
chosen for biological testing in order to advance the therapeutic process against malaria. …

… , as most current malaria chemotherapies suffer the same … therapy with artemisinin as the
central drug, artemisinin-based combination therapy (ACT), is currently the preferred malaria …

… in a given population [27], we apply an intervention strategy consisting of giving a varying
number of therapeutic courses of an anti-malarial drug. The model is represented by the …

… Despite its effectiveness, mupirocin is unfit to serve as a lead for anti-malarial therapy as it is
… published study [16] where two-step in silico screening (two-dimensional followed by three-…

… experiments for malaria therapy, we developed a ligand -based pharmacophore-model
and relying on the complex structure of PfDHODH and the ligand, pharmacophore-model was …

… malaria parasite. This systematic review evaluates the published research studies that
applied in silico modeling … articles using the search terms “Malaria” “In silico model”, “Computer-…

… in silico approaches. This review describes the peculiarities of malaria proteins and then
details various in silico … responses provide attractive targets for therapeutic interventions. In the …

… With the approach aiming at the identification of therapeutic targets to enhance this type of
… from the malaria subset of ChEMBL. Following this crucial step, predictive model building (b) …

… and severe falciparum malaria (referred to as uncomplicated and severe malaria henceforth)
… artemisinin combination therapy (ACT) for uncomplicated malaria and intravenous (iv) or …