[PDF][PDF] An overview on the mechanisms of solubility and dissolution rate enhancement in solid dispersion

S Sapkal, M Babhulkar, A Rathi, G Mehetre… - Int J Pharm Tech …, 2013 - researchgate.net
… In this article more emphasis given to the mechanisms by which solubility & dissolution rate
occurs in solid dispersions. The possible mechanisms may be by particle size reduction and …

Solid dispersions, part I: recent evolutions and future opportunities in manufacturing methods for dissolution rate enhancement of poorly water-soluble drugs

DN Bikiaris - Expert opinion on drug delivery, 2011 - Taylor & Francis
dissolution enhancement of SDs is based on the fact that drugs in the nanoscale range, or in
amorphous phase, dissolve … the drug and the mechanism of dissolution rate enhancement. …

Dissolution rate enhancement of loratadine in polyvinylpyrrolidone K-30 solid dispersions by solvent methods

F Frizon, J de Oliveira Eloy, CM Donaduzzi, ML Mitsui… - Powder technology, 2013 - Elsevier
dissolution rate is most likely the limiting step in the intestinal absorption [14]. Thus, the
dissolution rate enhancement is of … the enhancement in the dissolution rate of loratadine in solid

Solid dispersions, part II: new strategies in manufacturing methods for dissolution rate enhancement of poorly water-soluble drugs

DN Bikiaris - Expert opinion on drug delivery, 2011 - Taylor & Francis
dissolution rate enhancement of such drugs. Among such techniques, nanosuspensions
and drug formulation in solid … been applied for the dissolution enhancement of poorly water-…

[HTML][HTML] Formulation development and dissolution rate enhancement of efavirenz by solid dispersion systems

PT Koh, JN Chuah, M Talekar… - Indian journal of …, 2013 - ncbi.nlm.nih.gov
dissolution rate of efavirenz using solid dispersion systems (binary and ternary). A comparison
between solvent and fusion method was also investigated. Solidsolid dispersion system. …

Strongly enhanced dissolution rate of fenofibrate solid dispersion tablets by incorporation of superdisintegrants

P Srinarong, JH Faber, MR Visser, WLJ Hinrichs… - European Journal of …, 2009 - Elsevier
… was incorporated in the drug containing solid dispersions than when it was physically mixed
with the solid dispersions. The dissolution rate enhancement strongly depended on the type …

[PDF][PDF] Dissolution rate enhancement of alprazolam by solid dispersion

LK Roul, NK Manna, RN Parhi, S Sahoo… - Indian J. Pharm. Edu …, 2012 - researchgate.net
… When solubility and dissolution rate of solid dispersion of Alprazolam with PVP K30 were …
solid dispersion carrier seems more important for the initial enhancement of dissolution rate. …

[PDF][PDF] Solubility and dissolution rate enhancement of curcumin using kollidon VA64 by solid dispersion technique

S Ajay, D Harita, M Tarique, P Amin - Int J Pharm Tech Res, 2012 - researchgate.net
… and dissolution rate enhancement of curcumin by solid dispersion technique. For solid
dispersion preparation, Kollidon VA 64 polymer was selected as a hydrophilic carrier. Solid

Dissolution rate enhancement and physicochemical characterization of carbamazepine-poloxamer solid dispersions

DP Medarević, K Kachrimanis, M Mitrić… - Pharmaceutical …, 2016 - Taylor & Francis
… This study investigates the potential of poloxamers as solid dispersions (SDs) carriers in
improving the dissolution rate of a poorly soluble drug, carbamazepine (CBZ). Solid dispersions …

[PDF][PDF] Dissolution rate enhancement of aceclofenac by solid dispersion technique

S Kumar, SK Gupta, PK Sharma - Asian J. Pharm. Life Sci, 2011 - ajpls.org
rate of dissolution of drugs having limited watersolubility are frequently required [5]. Enhancement
in the dissolution rate … this characteristic such as solid dispersions, micronization, salt …