Solubility enhancement and application of cyclodextrins in local drug delivery

DH Kim, SE Lee, YC Pyo, P Tran, JS Park - Journal of Pharmaceutical …, 2020 - Springer
drug carriers by forming inclusion complexes to conjugate with many drugs, they have been
applied in many drug delivery … the role of CDs in local administration, the ways in which CDs …

[PDF][PDF] Solubility enhancement techniques: a review on conventional and novel approaches

YS Thorat, ID Gonjari, AH Hosmani - … journal of pharmaceutical sciences …, 2011 - Citeseer
drug delivery systems for poorly water-soluble drugs due to their ability to solubilize the drugs
in the oil phase, thus increasing their dissolution … diluted after oral administration below the …

Passive enhancement strategies in topical and transdermal drug delivery

J Hadgraft - International journal of pharmaceutics, 1999 - Elsevier
… Optimization of the applied formulation can improve release to the skin and the use of … the
solubility parameter of the skin lipids; the diffusing drug may then have an enhanced solubility

[PDF][PDF] Solubility enhancement techniques

VR Vemula, V Lagishetty, S Lingala - … pharmaceutical sciences review and …, 2010 - Citeseer
… CDs can also be utilized as permeation enhancer in pulmonary drug delivery systems.
Rifampicin is a so- called concentration-dependent antibiotic, the rate and extent of bacterial kill is …

[PDF][PDF] Solubility enhancement technique: a review

S Jagtap, C Magdum, D Jadge… - Journal of pharmaceutical …, 2018 - academia.edu
Drug Administration (FDA) and it classify the drug in to four classes according to permeability
and solubility. … Only by using traditional methods of solubility enhancement it is not possible …

Solubility enhancers for oral drug delivery: can chemical structure manipulation be avoided?

CK Kim, JS Park - American Journal of Drug Delivery, 2004 - Springer
… The aim of this article is to review ways in which the solubility of these highly lipophilic drugs
can be enhanced, with particular emphasis on those methods that do not alter the chemical …

A Review on: Solubility Enhancement Techniques.

AR Kale, S Kakade, A Bhosale - Journal of Current Pharma …, 2020 - search.proquest.com
… rate of poorly water soluble drugs. The BCS is … drug substance based on its aqueous
solubility and intestinal permeability. As for BCS class II & IV drugs rate limiting step is drug release

[PDF][PDF] Self emulsifying drug delivery system: A tool in solubility enhancement of poorly soluble drugs

K Sapra, A Sapra, SK Singh, S Kakkar - Indo Global J Pharm Sci, 2012 - academia.edu
… Comparison of self-micro emulsifying drug delivery system versus solid dispersion technology
used in the improvement of dissolution rate and bioavailability of vinpocetine. Yao Xue …

Drug solubility: importance and enhancement techniques

KT Savjani, AK Gajjar, JK Savjani - … Scholarly Research Notices, 2012 - Wiley Online Library
… The improvement of drug solubility thereby its oral bio-… of drug development process especially
for oral-drug delivery system. … to enhance the solubility of poorly water-soluble drugs. The …

[PDF][PDF] Review on solubility enhancement techniques for hydrophobic drugs

A Kumar, SK Sahoo, K Padhee, PS Kochar… - Pharmacie …, 2011 - researchgate.net
… Therefore, the improvement of drug solubility thereby its oral … of drug development process
especially for oral drug delivery … to enhance the solubility of poorly water soluble drug. The …