A four-component combination derived from Huang-Qin Decoction significantly enhances anticancer activity of irinotecan

XU Dou-Dou, HOU Xiao-Ying, W Ou, W Di… - Chinese Journal of …, 2021 - Elsevier
… 48 hours showed a synergism effect (CI < 1, Fig. 6). Synergism corresponding to CI < 1 always
… The CI value indicated a nearly additive effect at IC30 (0.90) and the synergistic effect got …

Synergistic Effect of Huangqin Decoction Combined Treatment With Radix Actinidiae chinensis on DSS and AOM-Induced Colorectal Cancer

J Huang, T Jiang, J Kang, J Xu, Y Dengzhang… - Frontiers in …, 2022 - frontiersin.org
… On basis of the earlier stage, this article intends to further clarify the prevention and treatment
effect of the Huangqin Tang with TLG on the type of damp–heat CRC through the mice …

Quantitative evaluation of the compatibility effects of huangqin decoction on the treatment of irinotecan-induced gastrointestinal toxicity using untargeted metabolomics

DN Cui, X Wang, JQ Chen, B Lv, P Zhang… - Frontiers in …, 2017 - frontiersin.org
Huangqin decoction consists of four medicinal herbs … to synergistic effects (Cheng, 2015).
For HQD, researches have revealed that Angelica dahurica extracts had synergistic action on S…

Systems pharmacology based strategy for Q-markers discovery of HuangQin decoction to attenuate intestinal damage

X Dai, D Cui, J Wang, W Zhang, Z Zhang… - Frontiers in …, 2018 - frontiersin.org
… was proposed to discover Q-marker of HuangQin decoction (HQD) to attenuate Intestinal
Damage. … and multi-target” mechanism of HQD and synergistic therapeutical effect on diarrhea. …

Huang-Lian Jie-Du decoction: a review on phytochemical, pharmacological and pharmacokinetic investigations

Y Qi, Q Zhang, H Zhu - Chinese medicine, 2019 - Springer
… components of HLJDD to reveal the chemical basis and synergistic actions contributing to
the pharmacological and clinically therapeutic effects. In this review, we summarized the main …

[HTML][HTML] Huangqin decoction alleviates lipid metabolism disorders and insulin resistance in nonalcoholic fatty liver disease by triggering Sirt1/NF-κB pathway

BF Yan, LF Pan, YF Quan, Q Sha… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Huangqin decoction (HQD), a Chinese medicinal formulation that has been used clinically
for thousands of years, has beneficial outcomes in patients with liver diseases, including …

A novel strategy for decoding and validating the combination principles of huanglian jiedu decoction from multi-scale perspective

KX Wang, Y Gao, WX Gong, XF Ye, LY Fan… - Frontiers in …, 2020 - frontiersin.org
huangqin and huanngbo in CTP network are 102.46 and 110.33, respectively. The degree
of targets of Huangqin … bioavailability or promoting the synergistic effect of different botanical …

[HTML][HTML] Huangqi Fuzheng decoction exerts antitumor activity by inhibiting cell growth and inducing cell death in osteosarcoma

J Qin, W Wang, L Sha, L Ge - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Huangqi Fuzheng decoction (HFD) is a traditional Chinese medicine and has been used as
adjuvant clinical therapy for breast, ovarian and thyroid cancer. However, the potential roles …

Herbal pair Huangqin-Baishao: mechanisms underlying inflammatory bowel disease by combined system pharmacology and cell experiment approach

X Huang, Z Chen, M Li, Y Zhang, S Xu… - … Medicine and Therapies, 2020 - Springer
… anti-inflammatory effect than their Q-markers, which might be due to their synergistic effect. …
Among them, HuangQin decoction (HQD) is a famous formula recorded in the Treatise on …

Exploring the Mechanisms of the Huangqin Qingfei Decoction in Pneumonia Treatment for Lipopolysaccharide-Induced Mouse Model: A Network Pharmacology …

Z Zheng, J Lei, J Chang, X Yi… - Natural Product …, 2024 - journals.sagepub.com
… However, the precise mechanisms underlying the synergistic effects of these 2 TCMs remain
incompletely understood. As such, further investigation is required to elucidate their anti-…