[HTML][HTML] Unlocking the therapeutic potential of primary tumor-draining lymph nodes

J Rotman, BD Koster, ES Jordanova… - Cancer Immunology …, 2019 - Springer
lymph nodes and distant organs. The sentinel lymph node (SLN) is the first node to receive
lymphatic … For many malignancies, the presence of tumor cells in tumor-draining lymph nodes

Lymphangiograms: their diagnostic and therapeutic potential

S Wallace, L Jackson, B Schaffer, J Gould… - Radiology, 1961 - pubs.rsna.org
… Lymphangiography can be used to determine the general type and extent of disease
processes; as a guide to lymph node dissection; in radiation therapy for portal placement; and in …

Therapeutic potential of oral tolerance

L Mayer, L Shao - Nature Reviews Immunology, 2004 - nature.com
lymph nodes 33,34 . Genetic or pharmacological deletion of the mesenteric lymph nodes
by phagocytic cells to the mesenteric lymph nodes through lymphatics (taken up through M …

[HTML][HTML] The potential therapeutic role of lymph node resection in epithelial ovarian cancer: a study of 13 918 patients

JK Chan, R Urban, JM Hu, JY Shin, A Husain… - British journal of …, 2007 - nature.com
lymph node dissections with a median number of six nodes reported. For all patients, a
more extensive lymph node … cancer to determine the potential role of lymph node dissection. …

Therapeutic differentiation and maturation of lymphatic vessels after lymph node dissection and transplantation

T Tammela, A Saaristo, T Holopainen, J Lyytikkä… - Nature medicine, 2007 - nature.com
lymph node dissection, we combined growth factor therapy … that VEGF-C therapy greatly
improves the outcome of lymph node … in lymphatic drainage function and preservation of normal …

[HTML][HTML] Lymph node metastasis in cancer progression: molecular mechanisms, clinical significance and therapeutic interventions

H Ji, C Hu, X Yang, Y Liu, G Ji, S Ge, X Wang… - … and Targeted Therapy, 2023 - nature.com
… The process of lymphangiogenesis is closely associated with the formation of new lymphatic
vessels within sentinel lymph nodes (SLN), ultimately supporting metastatic tumor spread. …

[HTML][HTML] Immunogenicity of protein therapeutics: a lymph node perspective

K Fu, K March, A Alexaki, G Fabozzi, E Moysi… - Frontiers in …, 2020 - frontiersin.org
… The lymph node structure/organization is shown. A zoomed T cell/follicular area with the …
The presence of therapeutic within the lymph node can initiate a cascade of immune reactions …

Generation of “LYmph Node Derived Antibody Libraries”(LYNDAL) for selecting fully human antibody fragments with therapeutic potential

P Diebolder, A Keller, S Haase, A Schlegelmilch… - MAbs, 2014 - Taylor & Francis
… To demonstrate the feasibility for selecting antibodies with therapeutic potential from these
… our approach to be useful for recovering fully human antibodies with therapeutic potential. …

[HTML][HTML] Lymph nodes and cancer metastasis: new perspectives on the role of intranodal lymphatic sinuses

RC Ji - International journal of molecular sciences, 2016 - mdpi.com
… development mechanisms and improve therapeutic approaches for human malignancy. … of
lymph node lymphatic endothelial cells (LN-LECs), the cells derived from intranodal lymphatic

Potential therapeutic role of para-aortic lymphadenectomy in node-positive endometrial cancer

A Mariani, MJ Webb, L Galli, KC Podratz - Gynecologic oncology, 2000 - Elsevier
… Of the 612 patients, 238 had hysterectomy only and 374 had histologic assessment of
regional lymph nodes (at least 1 pelvic or para-aortic node biopsy). The mean number of …