Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis

DJ Hicklin, LM Ellis - Journal of clinical oncology, 2005 - ascopubs.org
New blood vessel formation (angiogenesis) is a fundamental event in the process of tumor
growth and metastatic dissemination. Hence, the molecular basis of tumor angiogenesis has …

Role of angiogenesis in tumor growth and metastasis

J Folkman - Seminars in oncology, 2002 - Elsevier
Angiogenesis is required for invasive tumor growth and metastasis and … tumors are
severely restricted in their growth potential because of the lack of a blood supply. For tumors

Tumor angiogenesis: a possible control point in tumor growth

J Folkman - Annals of internal medicine, 1975 - acpjournals.org
… , solid tumors in a variety of experimental models fail to grow … This perspective of the manner
by which solid tumors grow … nature of tumor angiogenesis factor, to determine whether tumor

Scatter factor/hepatocyte growth factor in brain tumor growth and angiogenesis

R Abounader, J Laterra - Neuro-oncology, 2005 - academic.oup.com
… , and tumor-associated angiogenesis. Conversely, inhibition of SF/HGF and c-Met in
experimental tumor xenografts leads to inhibition of tumor growth and tumor angiogenesis. SF/HGF …

[HTML][HTML] Tumor angiogenesis

M Detmar - Journal of Investigative Dermatology Symposium …, 2000 - Elsevier
… -1 (TSP-1) and TSP-2 are expressed in normal skin and, when introduced into squamous
cell carcinomas, potently inhibit malignant tumor growth via inhibition of tumor angiogenesis. …

[HTML][HTML] Tumor growth and angiogenesis are dependent on the presence of immature dendritic cells

O Fainaru, N Almog, CW Yung, K Nakai… - The FASEB …, 2010 - ncbi.nlm.nih.gov
tumor growth in these mice. Because immature DCs actively promote angiogenesis and
tumor growth… this response, we conclude that angiogenesis is dependent on the presence of …

Dual role of macrophages in tumor growth and angiogenesis

C Lamagna, M Aurrand-Lions… - Journal of leukocyte …, 2006 - academic.oup.com
… on angiogenesis, and elevated numbers of macrophages … tumor angiogenesis and tumor
growth [2, 29]. Thus, the switch from antitumor immunity to tumor growth and angiogenesis

Mechanisms of angiogenesis and their use in the inhibition of tumor growth and metastasis

A Saaristo, T Karpanen, K Alitalo - Oncogene, 2000 - nature.com
… of a variety of angiogenic growth factors may decrease tumor growth, VEGF and its … -angiogenic
therapy. VEGF-negative embryonic stem cells and tumor cells grow poorly as tumors in …

Tumor angiogenesis

J Folkman - Advances in cancer research, 1985 - Elsevier
… Recent progress in understanding the role of angiogenesis in progressive tumor growth will
… However, in the case of four tumors, neither angiogenesis nor tumor growth was suppressed …

Overview of angiogenesis during tumor growth

D Ribatti, A Vacca - Angiogenesis: An Integrative Approach from Science …, 2008 - Springer
… blood vessel-dependent tumor growth as opposed to classic angiogenesis. These vessels
tumor mass angiogenesis occurs by the cooperative interaction of VEGF and Ang-. Tumor