Altered angiogenesis underlying age-dependent changes in tumor growth

R Pili, Y Guo, J Chang, H Nakanishi… - … the National Cancer …, 1994 - academic.oup.com
tumors is often slow and prolonged in the elderly. Transplantable murine tumors grow and
spread less readily in older mice … Neovascularization is crucial for the growth of solid tumors, …

… of nonselective cyclooxygenase inhibition with low-dose ibuprofen on tumor growth, angiogenesis, metastasis, and survival in a mouse model of colorectal cancer

M Yao, W Zhou, S Sangha, A Albert, AJ Chang… - Clinical cancer …, 2005 - AACR
… on tumor growth, immediately after cells were implanted sc into mice on day 1, we randomly
divided the mice … at a concentration of 1,360 mg/kg (10 mice/group). In a separate parallel …

… the death-promoting gene bax-alpha which is downregulated in breast cancer restores sensitivity to different apoptotic stimuli and reduces tumor growth in SCID mice.

RC Bargou, C Wagener, K Bommert… - The Journal of …, 1996 - Am Soc Clin Investig
… SCID mice. To test the effects of bax expression on tumor growth in vivo, we transplanted
bax-expressing clones of the breast cancer cell lines R30C and MCF-7 into SCID mice. As …

Role of natural killer cells in tumor growth and metastasis: C57BL/6 normal and beige mice

JE Talmadge, KM Meyers, DJ Prieur… - … of the National Cancer …, 1980 - academic.oup.com
tumor growth have been established (15). Therefore, this latent positive effect on tumor
growth in normal mice … Metastatic capabilities of the tumors were evaluated by two assays of …

Antioxidants accelerate lung cancer progression in mice

VI Sayin, MX Ibrahim, E Larsson, JA Nilsson… - Science translational …, 2014 - science.org
… of antioxidants on lung tumor growth occurs with a different oncogene and mouse line, we
… of human lung cancer cell lines via similar mechanisms as in mouse tumor cells, the precise …

… growth factor receptor signaling in tumor cells and tumor-associated endothelial cells for therapy of androgen-independent human prostate cancer growing in the …

SJ Kim, H Uehara, T Karashima, DL Shepherd… - Clinical cancer …, 2003 - AACR
… Purpose: We determined whether blockade of the epidermal growth factor receptor (EGF-R) …
Taxol inhibits the growth of PC-3MM2 human prostate cancer cells in the bone of nude mice. …

p53-dependent apoptosis suppresses tumor growth and progression in vivo

H Symonds, L Krall, L Remington, M Saenz-Robles… - Cell, 1994 - cell.com
cancer, ~53 mutations typically occur in late stages of tumor … , TgT12, p53-‘- mice developed
tumors at a rate comparable to … in tumor growth rate was observed when TgT12, mice were …

Humanized tumor mice—a new model to study and manipulate the immune response in advanced cancer therapy

AK Wege, W Ernst, J Eckl… - … journal of cancer, 2011 - Wiley Online Library
… Therefore, HTM makes it possible to study in vivo processes such as human tumor growth,
tumor burden, tumor-cell dissemination and metastasis (early on in lung and bone marrow) in …

Resolvins suppress tumor growth and enhance cancer therapy

ML Sulciner, CN Serhan, MM Gilligan… - Journal of Experimental …, 2018 - rupress.org
… we first developed a mouse debris-stimulated tumor model applicable to many cancer types
in … In this study, we demonstrate that tumor cell debris can stimulate tumor growth, which has …

IL-6 signaling promotes tumor growth in colorectal cancer

C Becker, MC Fantini, S Wirtz, A Nikolaev, HA Lehr… - Cell Cycle, 2005 - Taylor & Francis
… Similar to these observations in mice, here we show that human colon cancer tissue
expressed only low amounts of membrane bound IL-6R. In contrast, expression and activity of the …