… Cancer stem cells (CSCs) are a class of pluripotent cells that have been … cancers. CSCs
have been shown in numerous cancer models to be involved in tumor development, cell …

… In the “cancer stem cell model”, the cellular heterogeneity within the tumor is ascribed entirely
to the differentiating tumor cells that derive from the CSC. This phenomenon resembles the …

… requisite human support cells. Lastly, because the term “cancer stem cell” also currently
designates the normal cell that founded the tumor, we suggest that the cells sustaining growth of …

… or exclusively by a rare subpopulation, commonly termed “cancer stem cells.” Support for
the cancer stem cell model has been stimulated by experiments in which human tumor cells …

… Stem cells have been implicated in pancreatic tumor growth, but the specific role of these
cancer stem cells in tumor … human pancreatic cancer tissue contains cancer stem cells defined …

… cancer stem cells in every human cancer type. We present the current scientific evidence
supporting the cancer stem cell … implications of the discovery of human cancer stem cells. …

… stem cell seems to be related to their quiescent state. It is hard to target CSCs or CSC-rich
tumors, because these carcinoma stem cells can exit the cell … For some cancers, such as those …

… a ‘cancer stem cell’ (CSC) model – where cancer growth and/… subset of tumor cells that exhibit
properties similar to stem cells. … cancer therapies that target cells propelling cancer growth. …

… role of intrinsic cell properties and cell-cell interactions in tumor growth and morphological
… tumors in any organ. We propose that the tumor growth paradox within the cancer stem cell …

… cancer stem cell hypothesis on the origins of tumor heterogeneity, focusing both on heterogeneity
within the tumor cells … this subset of tumor cells will eliminate tumor growth in the long …