Type 2 inflammation in chronic rhinosinusitis without nasal polyps: another relevant endotype
T Delemarre, G Holtappels, N De Ruyck… - Journal of Allergy and …, 2020 - Elsevier
Background Chronic rhinosinusitis without nasal polyps (CRSsNP) is mainly considered a
type 1 mediated disease. The role and clinical significance of type 2 immune responses in
CRSsNP have not been addressed sufficiently; a recent cluster analysis for CRS described
the existence of a subgroup of patients with CRSsNP with a type 2 inflammation. Objective
We aimed to characterize the underlying type 2 immune response and its clinical
significance in patients with CRSsNP. Methods A total of 240 patients with CRSsNP were …
type 1 mediated disease. The role and clinical significance of type 2 immune responses in
CRSsNP have not been addressed sufficiently; a recent cluster analysis for CRS described
the existence of a subgroup of patients with CRSsNP with a type 2 inflammation. Objective
We aimed to characterize the underlying type 2 immune response and its clinical
significance in patients with CRSsNP. Methods A total of 240 patients with CRSsNP were …
以上显示的是最相近的搜索结果。 查看全部搜索结果