… arginase inhibition on blood pressure and vascular function in … first time the effects of arginase
inhibition on blood pressure (… Arginase inhibition was achieved by the selective arginase …

… However, arginase inhibition has no effect on the remodeling of … that arginase-mediated
vascular remodeling is vessel dependent in these animals. The ability of arginase inhibition to …

… function by arginase inhibition is age-dependent in elderly healthy individuals, suggesting
that arginase may … restores NOS coupling and reverses endothelial dysfunction and vascular …

… suggest that arginase inhibition improves vascular function across different vascular beds in
… -NOHA is non-selective for arginase isoforms, it is not clear whether it is arginase I or II that …

… demonstrate diminished NO release and NO-mediated dilation to adenosine that are partially
restored by arginase inhibition or by incubation with L-arginine (48). Furthermore, aortic …

… to improve endothelial function or cardiovascular outcomes in … that arginase inhibition
improves endothelial function beyond … T2DM for the improvement in vascular function. Moreover, …

… do not explain the response to arginase inhibition in the present study. During the … arginase
inhibition could be an effective pharmacological intervention to improve the vascular function …

… -specific arginase inhibitor with an IC50 value of 11.22 μM (arginase I) and 11.06 μM (arginase
II) … Therefore, statins, which are known to inhibit the Rho/Rock pathway, reduce vascular …

… to evaluate coronary microvascular function in type 2 … of arginase inhibition to restore
vascular function. Different groups of GK and Wistar rats were given vehicle, the arginase inhibitor …

… In conclusion, we present a novel arginase inhibitor, THSG, which enhanced vessel …
impaired vascular function in HCD-fed ApoE −/− mice. THSG-dependent inhibition of arginase …