Association of data-driven white matter hyperintensity spatial signatures with distinct cerebral small vessel disease etiologies

…, JM Lee, Alzheimer's Disease Neuroimaging Initiative - Neurology, 2022 - AAN Enterprises
… study on participants of the Alzheimer's Disease Neuroimaging Initiative (ADNI) to identify
… ), characterizing different forms of cerebral small vessel disease (CSVD) using multivariable …

Advanced neuroimaging to unravel mechanisms of cerebral small vessel diseases

ME Gurol, GJ Biessels, JR Polimeni - Stroke, 2020 - Am Heart Assoc
… A detailed review of molecular neuroimaging in vascular cognitive impairment, that included
… For this reason, the fundamentals of molecular neuroimaging will only be briefly discussed, …

Relationship between obstructive sleep apnea and neuroimaging signatures of cerebral small vessel disease in community-dwelling older adults. The Atahualpa …

OH Del Brutto, RM Mera, M Zambrano, PR Castillo - Sleep medicine, 2017 - Elsevier
… WMH but not with other neuroimaging signatures of SVD (namely… between OSA and imaging
signatures of SVD is inconsistent. … between OSA and neuroimaging signatures of SVD were …

[HTML][HTML] Genome-wide association study of MRI markers of cerebral small vessel disease in 42,310 participants

E Persyn, KB Hanscombe, JMM Howson… - Nature …, 2020 - nature.com
… Cerebral small vessel disease is a major cause of stroke and … Our aim is to better understand
the disease pathophysiology. … the biological mechanisms underlying small vessel disease. …

[HTML][HTML] Connectomic-genetic signatures in the cerebral small vessel disease

R Gutiérrez-Zúñiga, I Diez, E Bueichekú, CM Kim… - … of disease, 2022 - Elsevier
… In this study, the integration of neuroimaging connectivity SVD phenotypes and transcriptomic
data from the AHBA has helped us to identify several genetic signatures that might shed …

Metabolomic profiling in small vessel disease identifies multiple associations with disease severity

EL Harshfield, CJ Sands, AM Tuladhar, FE de Leeuw… - Brain, 2022 - academic.oup.com
… metabolic signatures that are associated with imaging markers of small vessel disease, …
and 85 years; and (ii) cerebral SVD on neuroimaging, defined as the presence of either WMH or …

Neuroimaging and neuropathology indices of cerebrovascular disease burden: a systematic review

MB Paradise, CE Shepherd, W Wen, PS Sachdev - Neurology, 2018 - AAN Enterprises
… In addition to the well-known consequences of large vessel disease such as stroke and
certain types of vascular dementia (VaD), the significance of small vessel disease (SVD) is being …

[HTML][HTML] Cerebral vascular dysfunctions detected in human small vessel disease and implications for preclinical studies

JM Wardlaw, H Benveniste… - Annual Review of …, 2022 - annualreviews.org
… means patients with clinical features or neuroimaging lesions of presumed vascular origin
… , in which ∼0.1 Hz may be a distinct signature frequency of arterioles (73) and may be …

Neuroimaging signatures of cerebral small vessel disease and risk of falls in stroke-free older adults living in rural Ecuador. The Atahualpa Project

OH Del Brutto, CD Peinado, RM Mera… - Journal of the …, 2019 - Elsevier
… This study aimed to assess the association between neuroimaging signatures of cerebral
small vessel disease (cSVD) and the risk of falls in stroke-free older adults living in rural …

Magnetic Resonance Imaging Tissue Signatures Associated With White Matter Changes Due to Sporadic Cerebral Small Vessel Disease Indicate That White Matter …

ACC Jochems, S Muñoz Maniega… - Journal of the …, 2024 - Am Heart Assoc
… We compared tissue signatures cross‐sectionally between areas, and longitudinally within
each area. WMH change masks were available for N=197. Participants' mean age was 65.61 …