… Vitamin B12 that contains a cyanide group in the upper axial ligand (cyanocobalamin) is
a … Derivatives of vitamin B12 of physiological importance are coenzyme B12 or adenosylco…

… of methylmalonylCoA, which occurs when a deficiency of B12 coenzyme exists, may lead
to its incorporation into fatty acids in place of malonyl-CoA. … the effect of methylmalonyl-CoA …

… that vitamin Bza coenzyme is a cofactor for the isomerization of methylmalonyl-CoA to
succinyl-CoA. … The vitamin B12 coenzyme was generously supplied by Merck, Sharp and Dohme …

… on the cellular CoA pool was studied in rats with functional vitamin B-12 deficiency induced
by … expected from decreased L-methylmalonylCoA mutase activity, with accretion ofpropionyl-…

… CoA -- succinyl CoA succinate. Isomerization of methylmalonyl CoA to succinyl CoA (… enzyme
catalyzing the carboxylation of propionyl CoA to methylmalonyl CoA) has been found to be …

… chemistry of vitamin B12, relevant in the context of the metabolic transformation of B12-derivatives
into the relevant coenzyme forms and their use in B12-dependent enzymes. …

… We wish to report that a coenzyme form of vitamin B12, 5,6 dimethylbenzimfdazolyl … the activity
of methylmalonyl-CoA … both in the absence or presence of vitamin B12, by 60 per cent and …

… manifestations associated with vitamin Blz deficiency is not … by vitamin Blz deficiency,
we have examined the distribution of vitamin Blz coenzyme and the activity of methylmalonyl-CoA …

… B 12 -linked enzyme, methylmalonyl-CoA mutase, was measured in vitro in seven patients
with vitamin B 12 deficiency (group I), six patients with anemia not due to vitamin B 12 lack (…

… Direct evidence for the conformational distortion of the corrin ring by the nucleotide base
in vitamin B 12 : synthesis and solution spectroscopic and crystal structure analysis of cob-…