… regulating the myocardial extracellular matrix during the natural history of aortic stenosis may
… more precise identification of the development of maladaptive left ventricular remodeling. …

Aortic stenosis (AS) causes left ventricular remodeling (hypertrophy, remodeling, fibrosis) and
other cardiac changes (left atrial dilatation, pulmonary artery and right ventricular changes)…

… human myocardial interstitial fibrosis in aortic stenosis (AS) is plastic and can regress. …
severe, symptomatic aortic stenosis were recruited (48% of all surgical aortic valve replacements […

… impact of left ventricular (LV) remodelling on diastolic … remodelling on clinical outcomes
before and after aortic valve replacement. The relative irreversibility of maladaptive remodelling …

… In order to study the effects of aortic stenosis on the ventricle in isolation, our cohort was …
of left ventricular remodeling. Exclusion criteria therefore included those with prior myocardial …

… since arterial dysfunction begin in early childhood in this population. Our data suggest that
the advanced cardiac remodeling and rapid onset of symptom cannot be explained by aortic …

… once left ventricular compensatory mechanisms fail. In this review, we describe the … ventricular
response to aortic stenosis. Specifically, we highlight the process of adaptive remodeling, …

… failure development and post-AVR cardiovascular events in patients with aortic stenosis.
Modified calcium handling, metabolic and electrical myocardial remodeling, diminished …

… Adverse left ventricular (LV) remodeling increases risk of cardiovascular events in aortic
stenosis (AS). Myocardial flow reserve (MFR), defined as stress divided by rest …

… to examine the association between the different patterns of left ventricular (LV)
remodelling/hypertrophy on all-cause and cardiovascular mortality in patients with aortic stenosis …