Overview of brain microdialysis
VI Chefer, AC Thompson, A Zapata… - Current protocols in …, 2009 - Wiley Online Library
… of tissue trauma on the interpretation of microdialysis results, … rate of DA uptake in the vicinity
of the microdialysis probe. This … magnitude of increase in dopamine uptake produced by nor-…
of the microdialysis probe. This … magnitude of increase in dopamine uptake produced by nor-…
Quantitative aspects of brain microdialysis
JL Peters, H Yang, AC Michael - Analytica chimica acta, 2000 - Elsevier
… Hence, our results show that recovery of dopamine from brain tissue by microdialysis probes
is an inefficient process and that blockade of the dopamine uptake mechanism increases …
is an inefficient process and that blockade of the dopamine uptake mechanism increases …
Microdialysis for pharmacokinetic analysis of drug transport to the brain
ECM de Lange, BAG de Boer, DD Breimer - Advanced drug delivery …, 1999 - Elsevier
… This inevitably causes brain tissue trauma and may therefore … if intracerebral microdialysis
provides meaningful data on … By using the brain perfusion technique and initial uptake of a …
provides meaningful data on … By using the brain perfusion technique and initial uptake of a …
Methodological considerations of intracerebral microdialysis in pharmacokinetic studies on drug transport across the blood–brain barrier
ECM de Lange, M Danhof, AG de Boer… - Brain research reviews, 1997 - Elsevier
… tissue trauma by intracerebral microdialysis a number of histological studies has been
performed 10, 26, 43, 44, 50, 82, 93. Early tissue reactions after 10 hr of continuous microdialysis …
performed 10, 26, 43, 44, 50, 82, 93. Early tissue reactions after 10 hr of continuous microdialysis …
Brain microdialysis and its applications in experimental neurochemistry
E Anderzhanova, CT Wotjak - Cell and tissue research, 2013 - Springer
… in vivo brain microdialysis, voltammetric methods, etc). We highlight practical aspects of
microdialysis … to increase the repertoire of their experimental techniques with brain microdialysis. …
microdialysis … to increase the repertoire of their experimental techniques with brain microdialysis. …
In vivo cellular uptake of glutamate is impaired in the rat hippocampus during and after transient cerebral ischemia: a microdialysis extraction study
T Bruhn, T Christensen… - Journal of Neuroscience …, 2001 - Wiley Online Library
… microdialysis in CA1 of the rat hippocampus, we studied the effect of transient cerebral
ischemia on in vivo uptake … to investigate uptake of glutamate in the intact rat brain in relation to …
ischemia on in vivo uptake … to investigate uptake of glutamate in the intact rat brain in relation to …
Cerebral uptake of drugs in humans
RN Upton - Clinical and experimental pharmacology and …, 2007 - Wiley Online Library
… Microdialysis was first described in 1974 as a method to … in subcutaneous tissues, but
further development saw microdialysis … This wider adoption of cerebral microdialysis probes in …
further development saw microdialysis … This wider adoption of cerebral microdialysis probes in …
Microdialysis versus other techniques for the clinical assessment of in vivo tissue drug distribution
M Brunner, O Langer - The AAPS journal, 2006 - Springer
… 18F-labeled ciprofloxacin in several tissues over several hours in healthy volunteers 56
and patients with foot infections, 63 and we have compared intracerebral uptake of 11C-labled …
and patients with foot infections, 63 and we have compared intracerebral uptake of 11C-labled …
A method to evaluate the diffusion rate of drugs from a microdialysis probe through brain tissue
BHC Westerink, JB De Vries - Journal of neuroscience methods, 2001 - Elsevier
… brain tissue, is not available at the present time. Here we describe a dual-probe microdialysis
… Rat brain nuclei that are infused by a microdialysis probe in dual–probe experiments have …
… Rat brain nuclei that are infused by a microdialysis probe in dual–probe experiments have …
Pharmacological mitigation of tissue damage during brain microdialysis
KM Nesbitt, A Jaquins-Gerstl, EM Skoda… - Analytical …, 2013 - ACS Publications
… DA uptake activity in the tissue nearby the microdialysis probes. This robust DA uptake activity
… The responses observed after uptake inhibition by nomifensine, therefore, more directly …
… The responses observed after uptake inhibition by nomifensine, therefore, more directly …
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