Weight loss induced by chronic dapagliflozin treatment is attenuated by compensatory hyperphagia in diet‐induced obese (DIO) rats

JJ Devenny, HE Godonis, SJ Harvey, S Rooney… - …, 2012 - Wiley Online Library
… to enhance dapagliflozin-induced weight loss by preventing … to dapagliflozin treatment, and
if so, whether prevention of hyperphagia would enhance dapagliflozin-induced weight loss in …

Dapagliflozin treatment in patients with different stages of type 2 diabetes mellitus: effects on glycaemic control and body weight

L Zhang, Y Feng, J List… - Diabetes, Obesity and …, 2010 - Wiley Online Library
weight, fasting plasma glucose, and urinary glucose excretion. After 12 weeks of dapagliflozin
treatment, A1c reduction, weight loss… the A1c reduction after dapagliflozin treatment with a …

Dapagliflozin‐induced weight loss affects 24‐week glycated haemoglobin and blood pressure levels

CD Sjöström, M Hashemi, J Sugg… - Diabetes, Obesity …, 2015 - Wiley Online Library
… In conclusion, dapagliflozin-mediated weight loss may … in weight is of benefit in patients
with diabetes 2. This analysis aimed to evaluate whether dapagliflozin-induced weight loss

Changes in weight loss‐related quality of life among type 2 diabetes mellitus patients treated with dapagliflozin

S Grandy, M Hashemi, AM Langkilde… - Diabetes, Obesity …, 2014 - Wiley Online Library
Dapagliflozin patients had significantly greater weight loss … of dapagliflozin-treated patients
reporting ongoing weight loss … 24, 50 and 102) than placebo-treated patients. In a post-hoc …

[HTML][HTML] Efficacy of the treatment with dapagliflozin and metformin compared to metformin monotherapy for weight loss in patients with class III obesity: a randomized …

A Ferreira-Hermosillo, MA Molina-Ayala… - Trials, 2020 - Springer
… Finally, we aim to investigate if dapagliflozin treatment increases insulin and glucagon
secretion in patients with obesity. Chronic hyperglycemia leads to a defect in insulin production …

[HTML][HTML] Dapagliflozin added to glimepiride in patients with type 2 diabetes mellitus sustains glycemic control and weight loss over 48 weeks: a randomized, double …

K Strojek, KH Yoon, V Hruba, J Sugg, AM Langkilde… - Diabetes Therapy, 2014 - Springer
… We have reported both analyses to evaluate the robustness of dapagliflozin treatment effects
and found that the adjusted mean changes from baseline in HbA 1c were similar between …

[HTML][HTML] The effect of dapagliflozin treatment on epicardial adipose tissue volume

T Sato, Y Aizawa, S Yuasa, S Kishi, K Fuse… - Cardiovascular …, 2018 - Springer
… Furthermore, the reduction of EAT volume might also be achieved with weight loss alone.
Therefore, this effect might not be specific to dapagliflozin. Fourth, the present study evaluated …

Effects of dapagliflozin on cardiovascular risk factors

A Ptaszynska, E Hardy, E Johnsson… - Postgraduate …, 2013 - Taylor & Francis
… In addition, dapagliflozin treatment facilitated weight loss in patients with T2DM by inducing
controlled glucosuria. Small changes in lipid levels, not likely to be of clinical significance, as …

Dapagliflozin: a review on efficacy, clinical effectiveness and safety

AJ Paisley, R Yadav, N Younis… - Expert opinion on …, 2013 - Taylor & Francis
… A particular benefit of dapagliflozin has been its ability to promote weight loss. Studies have
… •• This study reported on the efficacy and safety of dapagliflozin treatment in patients on …

Effects of Dapagliflozin, an SGLT2 Inhibitor, on HbA1c, Body Weight, and Hypoglycemia Risk in Patients With Type 2 Diabetes Inadequately Controlled on …

J Rosenstock, M Vico, LI Wei, A Salsali, JF List - Diabetes care, 2012 - Am Diabetes Assoc
… of dapagliflozin further reduced HbA 1c levels and mitigated the pioglitazone-related weight
gain … urinary excretion of glucose with modest caloric elimination leading to weight loss (2,3). …