Dapagliflozin, peptide YY, and weight loss in heart failure with preserved ejection fraction

YNV Reddy, V Melenovsky, AK Asokan… - European Heart …, 2024 - academic.oup.com
treatment with dapagliflozin for 24 weeks increased plasma PYY levels, and the extent of this
increase was correlated with weight loss, particularly adipose tissue loss, … to weight loss in …

Dapagliflozin for heart failure according to body mass index: the DELIVER trial

C Adamson, T Kondo, PS Jhund… - European heart …, 2022 - academic.oup.com
Treatment with dapagliflozin improves cardiovascular outcomes across the spectrum of BMI,
… , compared with those without, and has the additional benefit of causing modest weight loss. …

Dapagliflozin compared with other oral anti‐diabetes treatments when added to metformin monotherapy: a systematic review and network meta‐analysis

S Goring, N Hawkins, G Wygant… - Diabetes, Obesity …, 2014 - Wiley Online Library
… add-on treatment of … dapagliflozin was associated with significant weight loss whereas
sulphonylureas were associated with weight gain, and DPP-4 inhibitors were found to be weight

Efficacy of dapagliflozin in heart failure with reduced ejection fraction according to body mass index

C Adamson, PS Jhund, KF Docherty… - European journal of …, 2021 - Wiley Online Library
… , whereby the benefit of this treatment was greater in patients with larger waist … a treatment
anticipated to cause modest weight loss, 15, 16 according to baseline BMI in the Dapagliflozin

Dapagliflozin-induced long-term and severe anorexia and weight loss: An extraordinary case

E Cure, H Sirin, MC Cure, DA Sahin - Indian Journal of …, 2021 - journals.lww.com
… has an increasing effect on the patient's appetite and weight. However, the weight loss of
our patient continued despite the insulin treatment because her main problem was anorexia. …

No evidence of compensatory changes in energy balance, despite reductions in body weight and liver fat, during dapagliflozin treatment in type 2 diabetes mellitus: A …

SP Rajeev, CA Roberts, E Brown… - Diabetes, Obesity …, 2023 - Wiley Online Library
… between the estimated and actual weight loss because of dapagliflozin treatment in a
randomized, double-blind, placebo-controlled, cross-over trial. The results showed that …

… of exenatide once weekly plus dapagliflozin, exenatide once weekly, or dapagliflozin, added to metformin monotherapy, on body weight, systolic blood pressure, and …

SA Jabbour, JP Frías, C Guja, E Hardy… - Diabetes, Obesity …, 2018 - Wiley Online Library
… Body weight, SBP and triglyceride levels were reduced across most respective subgroups,
with no significant subgroup-by-treatment interactions. For each treatment, weight loss was …

Does dapagliflozin affect energy intake and appetite? A randomized, controlled exploratory study in healthy subjects

E Bertran, HD Berlie, A Nixon… - Clinical Pharmacology in …, 2019 - Wiley Online Library
… support this mechanism for weight loss discrepancy seen in … given dapagliflozin, caloric
restriction increased weight loss … therapy strategies to optimize weight loss in these patients. …

Efficacy and safety of dapagliflozin, a sodium glucose cotransporter 2 (SGLT2) inhibitor, in diabetes mellitus

P Fioretto, A Giaccari, G Sesti - Cardiovascular diabetology, 2015 - Springer
… of T1DM, and may be particularly appropriate in patients with T1DM treated with high doses
of insulin or who need weight loss. However, clinical trials in patients with T1DM are still …

Sodium-glucose cotransport inhibition with dapagliflozin in type 2 diabetes

JF List, V Woo, E Morales, W Tang… - Diabetes care, 2009 - Am Diabetes Assoc
… to total weight loss. Daily dapagliflozin was well tolerated with no major difference in adverse
events across treatment groups. The hypoglycemia experience supports the potential for …