Effects of the SGLT2 inhibitor dapagliflozin on energy metabolism in patients with type 2 diabetes: a randomized, double-blind crossover trial

YJM Op den Kamp, M de Ligt, B Dautzenberg… - Diabetes …, 2021 - Am Diabetes Assoc
weight of ∼1.5–2.0 kg during the treatment period, which is close to what we report here.
However, there was no significant effect of dapagliflozin treatment … most likely reflects a loss of …

Effect of dapagliflozin in patients with type 2 diabetes who have inadequate glycaemic control with glimepiride: a randomized, 24‐week, double‐blind, placebo …

K Strojek, KH Yoon, V Hruba, M Elze… - Diabetes, Obesity …, 2011 - Wiley Online Library
… tolerability of 24 weeks of dapagliflozin treatment as add-on therapy … who had been treated
with sulphonylurea monotherapy. … dapagliflozin induces weight loss may relate to caloric loss

Efficacy and safety of dapagliflozin monotherapy in people with type 2 diabetes: a randomized double‐blind placebo‐controlled 102‐week trial

CJ Bailey, EC Morales Villegas, V Woo… - Diabetic …, 2015 - Wiley Online Library
… In conclusion, dapagliflozin as monotherapy in treatment-naïve people with early Type 2
diabetes … and low rates of hypoglycaemia with the added benefit of weight loss over 102 weeks. …

… and safety of dapagliflozin in addition to insulin therapy in Japanese patients with type 2 diabetes: results of the interim analysis of 16‐week double‐blind treatment …

E Araki, Y Onishi, M Asano, H Kim… - Journal of diabetes …, 2016 - Wiley Online Library
… that the weight loss observed in the dapagliflozin group was partly as a result of fat loss. …
, which might also indicate a modest fluid loss by dapagliflozin-mediated osmotic diuresis. …

Dapagliflozin: a review of its use in patients with type 2 diabetes

GL Plosker - Drugs, 2014 - Springer
Dapagliflozin has a low risk of hypoglycaemia, although the … Dapagliflozin is not recommended
in patients with moderate … tolerability profile, dapagliflozin is a useful treatment option in …

Real-world effectiveness and safety of dapagliflozin therapy added to a GLP1 receptor agonist in patients with type 2 diabetes

JJ Gorgojo-Martinez, C Serrano-Moreno… - Nutrition, Metabolism …, 2017 - Elsevier
weight loss before starting dapagliflozin and lost less weight than patients without background
GLP1-RAs. Previous weight loss with a GLP1-RA might make further weight … body weight

Effects of exenatide once weekly plus dapagliflozin, exenatide once weekly alone, or dapagliflozin alone added to metformin monotherapy in subgroups of patients …

JP Frías, E Hardy, A Ahmed, P Öhman… - Diabetes, Obesity …, 2018 - Wiley Online Library
weight by sex (P = .099), with greater weight loss for women vs men across all treatments
(… In conclusion, treatment with exenatide once weekly plus dapagliflozin reduced HbA1c and …

Dapagliflozin: potential beneficial effects in the prevention and treatment of renal and cardiovascular complications in patients with type 2 diabetes

P Fioretto, A Avogaro - Expert Opinion On Pharmacotherapy, 2017 - Taylor & Francis
… , and diabetes treatments that work through insulin signaling are associated with weight gain.
The glucosuria-mediated weight loss observed with dapagliflozin as monotherapy or as an …

Dapagliflozin versus glipizide as add-on therapy in patients with type 2 diabetes who have inadequate glycemic control with metformin: a randomized, 52-week …

MA Nauck, S Del Prato, JJ Meier… - Diabetes …, 2011 - Am Diabetes Assoc
treatment led to weight gain and more hypoglycemic episodes, dapagliflozin produced
significant weight lossDapagliflozin treatment was generally safe and well tolerated, but events …

Dapagliflozin for the treatment of chronic kidney disease

Y Kurata, M Nangaku - Expert Review of Endocrinology & …, 2022 - Taylor & Francis
… Body weight Dapagliflozin treatment results in body weight loss of 2–3 kg in patients with
type 2 diabetes (baseline body weight 80–90 kg) [Citation65]. According to an RCT involving …