… doses of LAAM and methadone and also examined the ability of naloxone to reverse their
effects. Five occasional opioid users received once weekly doses … acute dosing conditions. For …

… optimal dose, we tested the interaction of condition (LAAM versus MM) and treatment retention
(status at 26 weeks) to determine whether LAAM's effect on opiate use was contingent on …

… Importantly, our study was conducted under naturalistic conditions, using rapid LAAM
induction schedules and individually titrated doses and where, as is the case in usual practice, …

… of oral methadone and LAAM administered under acute dosing and double blind experimental
conditions, produced at least the same magnitude of effect, as assessed by a range of …

… Methods: Eighty-four opioid addicts in ongoing maintenance treatment with stable methadone
doses were treated with methadone under study conditions for 5 weeks (run-in phase), …

… arrhythmias under methadone medication have predominantly been observed under high
dosages (markedly more than 100 mg per day) [28], whereas mean daily methadone dosage …

… The dissolution rate of LEVO was increased with α-… immediate-release tablets and capsule
dosage forms 2 in which DOPA-… under moist conditions to form dark-colored melanins. When …

… Early investigators demonstrated that high doses of levo-dihydoxyphenylalanine (L-dopa)
could provide benefits for patients with Parkinson's disease (PD),1-3 and that dopaminergic …

… dosage administration (three times weekly rather than daily), and a reduced potential for
withdrawal late in the inter-dosing … of oral LAAM under normal conditions, as well as during …

… There were relatively few significant differences in treatment retention among the agonist
medications under the reported study conditions, which were mainly dose-controlled and …