Levoalpha‐acetylmethadol (LAAM) versus methadone: treatment retention and opiate use

D Longshore, J Annon, MD Anglin, RA Rawson - Addiction, 2005 - Wiley Online Library
… seeking LAAM or methadone maintenance. Intervention LAAM or methadone maintenance,
plus ancillary services available to all patients. LAAM and methadone dose levels varied …

Relative potency of levo-α-Acetylmethadol and methadone in humans under acute dosing conditions

T Eissenberg, ML Stitzer, GE Bigelow… - … of Pharmacology and …, 1999 - ASPET
levo-α-Acetylmethadol (LAAM) and methadone are full μ-… LAAM is less potent than methadone.
Clinical studies have not … of acute doses of LAAM and methadone and also examined the …

Evaluation of levo-alpha-acetylmethdol (LAAM) as an alternative treatment for methadone maintenance patients who regularly experience withdrawal: a …

DAL Newcombe, F Bochner, JM White… - Drug and Alcohol …, 2004 - Elsevier
methadone with second daily levo-alpha-acetylmethadol (LAAM) would convert non-holders
on methadone … profiles of (R)-methadone with LAAM and its two metabolites. Sixteen stable …

Levoalpha‐acetylmethadol (LAAM) versus methadone maintenance: 1‐year treatment retention, outcomes and status

MD Anglin, BT Conner, J Annon, D Longshore - Addiction, 2007 - Wiley Online Library
… : methadone and levo-alpha-acetylmethadol (LAAM). LAAM, a longer-acting medication than
methadone, … Of these three, methadone maintenance (MM), first developed and used in the …

Metabolism of methadone andlevo-α-acetylmethadol (LAAM) by human intestinal cytochrome P450 3A4 (CYP3A4): potential contribution of intestinal metabolism to …

Y Oda, ED Kharasch - Journal of Pharmacology and Experimental …, 2001 - ASPET
Methadone and levo-α-acetylmethadol (LAAM) … methadone and LAAM. The purpose of the
present study is to test the hypothesis that methadone and LAAM are metabolized by human

Failure of methadone and levomethadyl acetate (levo-alpha-acetylmethadol, LAAM) maintenance to affect memory

P Grevert, B Masover, A Goldstein - Archives of General …, 1977 - jamanetwork.com
… to 30 patients taking methadone hydrochloride and 31 taking levomethadyl acetate (levo-alpha-…
The methadone and control groups also did not differ significantly in the frequency of …

A randomized, open-label trial comparing methadone and levo-alpha-acetylmethadol (LAAM) in maintenance treatment of opioid addiction

J Wolstein, M Gastpar, T Finkbeiner… - …, 2009 - thieme-connect.com
… LAAM and methadone in patients with … methadone doses were treated with methadone
under study conditions for 5 weeks (run-in phase), then randomly assigned to a methadone (n=41…

Role of human placental efflux transporter P-glycoprotein in the transfer of buprenorphine, levo-α-acetylmethadol, and paclitaxel

IA Nekhayeva, TN Nanovskaya… - American journal of …, 2006 - thieme-connect.com
… l-α-acetylmethadol (LAAM), a congener of methadone that has … of the therapeutic agent,
methadone or BUP, in the fetal … Human placenta plays an important role in protecting the …

An examination of the pharmacodynamics and pharmacokinetics of Levo-alpha-acetylmethadol (LAAM), compared to methadone, in opioid maintenance patients

DAL Newcombe - 2006 - hekyll.services.adelaide.edu.au
… of methadone .............. 32 1.4.1.2.4. The influence of extrinsic factors on methadone
pharmacokinetics33 … Pharmacodynamic effects during repeated dosing of methadone........... 34 …

Clinical experiences with 959 opiod-dependent patients treated with levo-alpha-acetymethadol (LAAM)

FS Tennant Jr, RA Rawson, E Pumphrey… - Journal of substance …, 1986 - Elsevier
… ble to that observed in our facilities for methadone maintenance subjects. For example,
during the first five months of 1985,200 methadone maintenance patients from two of the same …