Surfactant therapy for acute lung injury and acute respiratory distress syndrome

K Raghavendran, D Willson… - Critical care …, 2011 - criticalcare.theclinics.com
… of acute pulmonary injury are frequently defined as the syndromes of acute lung injury (ALI) …
The AECC definitions are often supplemented by lung injury or critical care scores such as …

Clinical review: Exogenous surfactant therapy for acute lung injury/acute respiratory distress syndrome-where do we go from here?

A Dushianthan, R Cusack, V Goss, AD Postle… - Critical Care, 2012 - Springer
… of surfactant biology in patients or an absence of therapeutic effect in this population…
Crucially, the mechanism of lung injury in neonates is different from that in ARDS: surfactant

The role of exogenous surfactant in the treatment of acute lung injury

JF Lewis, R Veldhuizen - Annual review of physiology, 2003 - annualreviews.org
… exogenous surfactant as a therapy for thissyndrome. Clinical experience with surfactant therapy
… the nature of the injury at the time oftreatment, the specific surfactant preparation utilized, …

Surfactant in respiratory distress syndrome and lung injury

M Hallman, V Glumoff, M Rämet - … and Physiology Part A: Molecular & …, 2001 - Elsevier
… -alveolar surfactant. New applications of surfactant-oriented therapies in RDS and other lung
and … -based progress on surfactant, highlighting the introduction of surfactant therapy, and …

Role of exogenous surfactant in acute lung injury

JF Lewis, A Brackenbury - Critical care medicine, 2003 - journals.lww.com
… Moreover, due to the adsorption and dispersal properties of surfactant, it is conceivable
that surfactant therapy may also be useful for delivery of other agents such as antibiotics, …

Surfactant replacement therapy in lung injury

PR Chess, JN Finkelstein, BA Holm - Lung Injury, 2005 - api.taylorfrancis.com
… examines exogenous surfactant therapy and its utility in mitigating clinical acute lung injury
(… tor-induced surfactant dysfunction in lung injury can be reversed or mitigated by increasing …

Surfactant use for neonatal lung injury: beyond respiratory distress syndrome

NN Finer - Paediatric Respiratory Reviews, 2004 - Elsevier
… Summary Surfactant has led to a significant reduction in neonatal mortality for premature
infants with lung immaturity and respiratory distress. However, surfactant therapy has been …

Surfactant replacement therapy reduces acute lung injury and collapse induration-related lung remodeling in the bleomycin model

L Steffen, C Ruppert, HG Hoymann… - … of Physiology-Lung …, 2017 - journals.physiology.org
… Collapse induration also occurs in acute interstitial lungsurfactant dysfunction aggravates
lung injury and early remodeling resulting in collapse induration within 7 days after lung injury

The future of exogenous surfactant therapy

DF Willson, RH Notter - Respiratory Care, 2011 - rc.rcjournal.com
… the evidence for surfactant dysfunction in acute lung injury (ALI) and … surfactant therapy in
term infants, children, and adults. While therapeutic use of surfactant in acute pulmonary injury

The future of surfactant therapy for patients with acute lung injury–new requirements and new surfactants

RG Spragg - Neonatology, 2002 - karger.com
… when designing trials of new lung surfactants for patients with acute lung injury (ALI). …
of surfactant therapy for ALI are examining the efficacy of a natural surfactant, a surfactant