… on the metabolic activation of morphine to reactive metabolites in vivo following morphine
… with rat liver microsomes, indicate that metabolic activation could contribute at least in part if …

… In hippocampus of chronic morphine-treated mouse, the expression levels of E2 component
… metabolism. Their finding directly links chronic morphine treatment to energy metabolism …

… reflect hepatic metabolism of morphine and that the morphine … metabolism the systemic
bioavailabilty is low and variable (1947%) (10-12). The predominant metabolic fate of morphine …

… in studying whether morphine and naloxone share the same metabolic … Similar to the findings
for morphine, the naloxone metabolism values … of the brain metabolism can be assessed. …

… We recently reported that morphine (I) is metabolized by … adduct of morphine using rat liver
microsomal incubations and … are capable of catalyzing the oxidation of morphine at the C-10 ‘…

… morphine has a hepatotoxic effect, that the morphine-induced hepatotoxicity is due to its
metabolic activation… In this paper, we examine the metabolism of morphine in freshly isolated rat …

… can be gained from studies of morphine or heroin metabolism [9]. … We limited our review to
morphine and heroin metabolism … of morphine metabolism in man, like any metabolic process, …

… Data suggest that, in severe liver disease, glucuronidation may be impaired, but in milder
disease, this metabolic pathway may be preserved. Extrahepatic metabolism of morphine may …

… altered MS-evoked changes in cerebral metabolism, by comparing LCMR glu in brain …
We were interested not only in which brain structures had an altered metabolic response to …

… In conclusion, the metabolic pathway of morphine to morphinone, a toxic metabolite, in …
Accordingly, the present study demonstrating the hepatic metabolism of morphine to morphinone …