… morphine was undetectable. Our data prove for the first time that dopamine is necessary for
morphine formation in vivo in mouse brain… an alternative route to dopamine formation. But the …

… The present review describes endogenous morphine and morphine … vivo study showed
that mice with a disrupted tyrosine hydroxylase gene were unable to synthesize EM in the brain (…

… metabolism of morphine to morphinone in rat was conŪrmed by in vivo and in vitro experiments.
… this pathway is a common route in morphine metabolism in several mammalian species. …

… formation of morphine and naloxone was studied in vitro after incubation of the brain …
Similarly, our present finding of a brain UDP-GT system is of special interest, since formation of the …

… morphine could be synthesized in animals has long been considered' and a pathway in
mammalian brain … We now report the conversion in vivo and in vitro of reticuline to salutaridine …

… mouse brain. In conclusion, the presence of endogenous morphine-like compounds in brain
… An identical result was obtained with brain tissue from mice perfused with PFA (in vivo; data …

… M3G has been found to antagonise morphine and M6G … M3G may influence the development
of morphine tolerance. M3G … , in vitro M6G was found to be only equipotent with morphine …

… fluids contain trace amounts of morphine. Its origin in mammals has been believed to be of
dietary origin. Here, we address the question of whether morphine is of endogenous origin or …

… Endogenous morphine is present in the mammalian brain as … in vivo leads to the formation
of morphine [26]. Ascaris suum, a mammalian parasite produces morphine in mammalian …

… In vitro recovery of morphine and morphine metabolites through the dialysis probe: In vitro
recovery of M, M3G and M6G through the dialysis membrane was determined by using 6 …