… increase in morphine levels near the trauma site in the brain compared to uninjured brain
tissue. … In this report, we present the pharmacokinetics of morphine in the human brain and the …

… On the other hand, in patients with focal brain lesions the contralateral hemisphere may …
normal piglet brain. The average morphine plasma clearance of 119 l h −1 in the patients in this …

… morphine analgesia may be profoundly influenced by the type of pain which is examined. We
have recently made large lesions … , lesions of either area attenuated the effects of morphine …

… Respiratory depression caused by morphine occurred in two of our patients. … morphine
injection during a reservoir refill [23]. The second occurred during escalation of im bolus morphine …

… morphine is administered to patients may either obey an active efflux of morphine metabolism
in a healthy brain … upstream morphine absorption in focal mass lesions and brain swelling. …

… the cerebrospinal fluid distribution of morphine, morphine-3-glucuronide, and morphine-6-…
cytokine interleukin-6 and the passive marker of blood-brain barrier permeability, albumin. …

… In the current study, the reduction of allodynia was similar in patients with spinal or supraspinal
lesions. Thus, it can thus be proposed that similar pathophysiologic mechanisms such as …

… , the patient accidentally overdosed on morphine pills and he was found unresponsive at
home. The patient was … Initial laboratory testing confirmed the presence of morphine in the urine …

… Disruption of the descending projections from the RVM by bilateral lesions of the dorsolateral
funiculus (DLF) also abolished morphine-induced abnormal pain and antinociceptive …

… A systematic study of the responsiveness to morphine in a group of post-stroke pain
patients with radiologically demonstrated lesions in the thalamic or suprathalamic regions has …