A rapid and sensitive quantitation method of endogenous morphine in human plasma

Y Liu, TV Bilfinger, GB Stefano - Life sciences, 1996 - Elsevier
… The results showed that the recovery of morphine by this technique was 86+… method increased
the detection limit by 40-fold. With this method the concentration of endogenous morphine

The presence of morphine in ganglionic tissues of Modiolus deminissus: A highly sensitive method of quantitation for morphine and its derivatives

Y Goumon, F Casares, W Zhu, GB Stefano - Molecular brain research, 2001 - Elsevier
… We demonstrated the presence of endogenous morphine and its metabolite M6G in the
pedal ganglia of the bivalve mollusk Modiolus deminissus by a new HPLC technique. The …

Endogenous morphine

GB Stefano, Y Goumon, F Casares, P Cadet… - Trends in …, 2000 - cell.com
… It is now well accepted that endogenous morphine is present in animals, both in … This
article examines morphine as an endogenous signaling molecule, in terms of its role in …

[PDF][PDF] Chemical characterization and regulation of endogenous morphine and codeine in the rat.

J Donnerer, G Cardinale, J Coffey, CA Lisek… - … of Pharmacology and …, 1987 - Citeseer
… The rat chow did not contain morphine or codeine as measured … only cxtracted free
morphine and we found the levels of free morphine in tissues to be very low (Donnerer …

Endogenous morphine and codeine in the brain of non human primate

C Neri, M Guarna, E Bianchi, D Sonetti… - Medical Science …, 2004 - usiena-air.unisi.it
… Materials/Methods: The presence of endogenous morphine and … The release of endogenous
morphine from monkey brain … Endogenous morphine, and its direct precursor codeine, was …

Morphine and its metabolites: Analytical methodologies for its determination

ME Bosch, AR Sanchez, FS Rojas, CB Ojeda - Journal of pharmaceutical …, 2007 - Elsevier
… An extremely sensitive method for the detection of endogenous morphine in plasma (80 pg
ml … analogous in hair with 10% HCl for 1 h at 100 C gave a quantitative recovery of morphine. …

Quantification of morphine, morphine 6-glucuronide, buprenorphine, and the enantiomers of methadone by enantioselective mass spectrometric chromatography in …

DJ Christoffersen, C Brasch-Andersen… - … Science, Medicine, and …, 2015 - Springer
… was to develop a method for quantitation of R- and S-methadone, morphine, M6G, and … lysis,
and endogenous and exogenous bacteria cause putrefaction. Quantitative analysis of blood …

Validation of a HPLC/MS method for simultaneous quantification of clonidine, morphine and its metabolites in human plasma

F Tang, H Bada, CM Ng… - Biomedical …, 2019 - Wiley Online Library
… range of quantitation was 1–1000 ng/mL for morphine, morphine-… This method was able
to separate structurally similar … of morphine and minimize interference from endogenous

Presence of endogenous morphine and morphine 6 glucuronide in human heart tissue

W Zhu, TV Bilfinger, G Baggerman… - International …, 2001 - spandidos-publications.com
… the opiate alkaloids morphine and morphine 6 glucuronide as … This method found endogenous
morphine and morphine 6 … did not contain morphine as determined by these methods. …

Direct quantification of morphine glucuronides and free morphine in urine by liquid chromatography–tandem mass spectrometry

K Deventer, OJ Pozo, FT Delbeke, P Van Eenoo - Forensic Toxicology, 2012 - Springer
… the sum of morphine, M3G, and M6G exceeds 1 μg/ml. Therefore, the quantitative method
must be … due to the absence of endogenous morphine isomers also excreted as glucuronides. …