Presence of reticuline in rat brain: A pathway for morphine biosynthesis
… small and large intestine and bacteria cultured from these tissues did not contain either
morphine or … that morphine biosynthesis may occur in rat neural tissues, and that its biosynthesis …
morphine or … that morphine biosynthesis may occur in rat neural tissues, and that its biosynthesis …
Effect of chronic morphine treatment on the biosynthesis of agmatine in rat brain and other tissues
F Aricioglu-Kartal, S Regunathan - Life sciences, 2002 - Elsevier
… if exposure to morphine could alter the metabolism of agmatine in rat brain as such changes
… in morphine dependence/withdrawal status. We report that rats exposed to morphine have …
… in morphine dependence/withdrawal status. We report that rats exposed to morphine have …
The effect of morphine on rat brain catecholamines: turnover in vivo and uptake in isolated synaptosomes
DH Clouet, JC Johnson, M Ratner, N Williams… - Frontiers in …, 1973 - Elsevier
… biosynthesis in the same area. In tolerant animals, the biosynthesis of DA was increased
in all areas of rat brain… during morphine treatment, the levels were increased in some brain …
in all areas of rat brain… during morphine treatment, the levels were increased in some brain …
Morphine: new aspects in the study of an ancient compound
S Benyhe - Life sciences, 1994 - Elsevier
… biosynthetic pathways for morphine exist in animal and even human tissues such as liver,
blood and brain… of which are identical to morphine) to rat brain synaptic plasma membrane …
blood and brain… of which are identical to morphine) to rat brain synaptic plasma membrane …
Effects of morphine, in vitro and in vivo, on tyrosine hydroxylase activity in rat brain
TJ Cicero, CE Wilcox, BR Smithloff, ER Meyer… - Biochemical …, 1973 - Elsevier
… activity of the enzyme were determined in several regions of rat brain. … To determine whether
morphine enhanced … biosynthesis in the rat brain, rats were injected with either 0 (saline), …
morphine enhanced … biosynthesis in the rat brain, rats were injected with either 0 (saline), …
Effects of morphine treatment on pro-opiomelanocortin systems in rat brain
DM Bronstein, R Przewlocki, H Akil - Brain research, 1990 - Elsevier
… estimate the dynamics of endogenous opioid biosynthesis. In the present studies, we re-examined
the question of morphine's effects on brain opioid systems, focusing in particular on …
the question of morphine's effects on brain opioid systems, focusing in particular on …
Synthesis of the skeleton of the morphine molecule by mammalian liver
CJ Weitz, KF Faull, A Goldstein - Nature, 1987 - nature.com
… by rat liver, but this conversion is not detectable in rat brain … hypothesis that morphine and
codeine in brain and adrenal … morphinan biosynthesis, we administered ["H]reticuline to rats …
codeine in brain and adrenal … morphinan biosynthesis, we administered ["H]reticuline to rats …
Catecholamine biosynthesis in brains of rats treated with morphine
DH Clouet, M Ratner - Science, 1970 - science.org
… morphine suggests that in the brains of tolerant rats, the catecholamine biosynthetic pathway
operates more effectively than it does in the brains of naive rats. … whole brain of tolerant rats …
operates more effectively than it does in the brains of naive rats. … whole brain of tolerant rats …
Biosynthesis of morphine in the animal kingdom
HW Kosterlitz - Nature, 1987 - nature.com
… codeine and free morphine in extracts of rat brain. Because in the morphine biosynthesis
of … in extracts of bovine adrenal gland and rat brain. Even then they still could not decide …
of … in extracts of bovine adrenal gland and rat brain. Even then they still could not decide …
De novo biosynthesis of morphine in animal cells: An evidence-based model
RM Kream, GB Stefano - Medical Science Monitor, 2006 - medscimonit.com
… licated and extended the original anatomical observations of Spector and coworkers by
demonstrating uptake and accumulation of 3H-labeled morphine within defined rat brain areas […
demonstrating uptake and accumulation of 3H-labeled morphine within defined rat brain areas […
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