Morphine‐induced changes of gene expression in the brain
S Ammon‐Treiber, V Höllt - Addiction biology, 2005 - Wiley Online Library
Repeated opiate administration alters gene expression in different brain regions of rodents,
an effect which may contribute to plastic changes associated with addictive behaviour. There …
an effect which may contribute to plastic changes associated with addictive behaviour. There …
Opioid abuse and brain gene expression
R Przewlocki - European journal of pharmacology, 2004 - Elsevier
Opiate addiction is a central nervous system disorder of unknown mechanism. Neuronal
basis of positive reinforcement, which is essential to the action of opioids, relies on activation …
basis of positive reinforcement, which is essential to the action of opioids, relies on activation …
The molecular mechanisms of morphine addiction
CA McClung - Reviews in the Neurosciences, 2006 - degruyter.com
Addiction to opiates such as morphine is a major public health concern. A more thorough
understanding of the molecular mechanisms of opiate addiction can lead to better treatment …
understanding of the molecular mechanisms of opiate addiction can lead to better treatment …
Behavioral and transcriptional patterns of protracted opioid self‐administration in mice
Chronic exposure to opioids induces adaptations in brain function that lead to the formation
of the behavioral and physiological symptoms of drug dependence and addiction. Animal …
of the behavioral and physiological symptoms of drug dependence and addiction. Animal …
Microarray analysis of genes expressed in the frontal cortex of rats chronically treated with morphine and after naloxone precipitated withdrawal
S Ammon, P Mayer, U Riechert, H Tischmeyer… - Molecular brain …, 2003 - Elsevier
Opioid dependence may be associated with adaptive changes in gene expression in the
brain. In the present study we used DNA microarrays (U34A; Affymetrix) to analyze the …
brain. In the present study we used DNA microarrays (U34A; Affymetrix) to analyze the …
Effects of morphine on immediate-early gene expression in the striatum of C57BL/6J and DBA/2J mice
B Ziółkowska, M Korostyński, M Piechota, J Kubik… - Pharmacological …, 2012 - Elsevier
Background Immediate early gene (IEG) induction elicited by drugs of abuse may contribute
to development of plastic changes in the brain responsible for drug-induced behavioral …
to development of plastic changes in the brain responsible for drug-induced behavioral …
Effects of chronic morphine and morphine withdrawal on gene expression in rat peripheral blood mononuclear cells
S Desjardins, E Belkai, D Crete, L Cordonnier… - …, 2008 - Elsevier
Chronic morphine treatment alters gene expression in brain structures. There are increasing
evidences showing a correlation, in gene expression modulation, between blood cells and …
evidences showing a correlation, in gene expression modulation, between blood cells and …
Gene expression profiling following short-term and long-term morphine exposure in mice uncovers genes involved in food intake
Addictive drugs including opioids activate signal transduction pathways that regulate gene
expression in the brain. However, changes in CNS gene expression following morphine …
expression in the brain. However, changes in CNS gene expression following morphine …
Regulation of gene expression by chronic morphine and morphine withdrawal in the locus ceruleus and ventral tegmental area
CA McClung, EJ Nestler, V Zachariou - Journal of Neuroscience, 2005 - Soc Neuroscience
Morphine dependence is associated with long-term adaptive changes in the brain that
involve gene expression. Different behavioral effects of morphine are mediated by different …
involve gene expression. Different behavioral effects of morphine are mediated by different …
Morphine exposure and abstinence define specific stages of gene expression in the rat nucleus accumbens
S Spijker, SWJ Houtzager, MCM De Gunst… - The FASEB …, 2004 - Wiley Online Library
Intermittent exposure to addictive drugs causes long‐lasting changes in responsiveness to
these substances due to persistent molecular and cellular alterations within the meso …
these substances due to persistent molecular and cellular alterations within the meso …
相关搜索
- gene expression in the brain
- long term morphine exposure
- locus ceruleus chronic morphine
- long term food intake
- food intake morphine exposure
- molecular mechanisms morphine addiction
- gene expression chronic morphine
- gene expression morphine withdrawal
- gene expression effects of morphine
- gene expression morphine exposure
- gene expression locus ceruleus
- locus ceruleus morphine withdrawal
- short term morphine exposure