Aims Haemodynamics alone do not fully explain symptoms and prognosis in clinically
severe aortic stenosis (AS). Myocardial disease, specifically diffuse myocardial fibrosis …

Objectives: This study assessed diffuse myocardial fibrosis (MF) by cardiac magnetic
resonance (CMR) imaging and speckle-tracking echocardiography (STE) in patients with …

Objectives The aim of this study was to investigate the relationship between extracellular
volume fraction (ECV), a noninvasive parameter that quantifies the degree of diffuse …

Objectives: Cardiac magnetic resonance (CMR) was used to investigate the extracellular
compartment and myocardial fibrosis in patients with aortic stenosis, as well as their …

Aims To investigate myocardial fibrosis (MF) in a large series of severe aortic stenosis (AS)
patients using invasive biopsy and non-invasive imaging. Methods and results One hundred …

BACKGROUND: Chronic aortic valve disease (AVD) is characterized by progressive
accumulation of interstitial myocardial fibrosis (MF). However, assessment of MF …

Background—Diffuse myocardial fibrosis is a final end point in most cardiac diseases. It is
missed by the cardiovascular magnetic resonance (CMR) late gadolinium enhancement …

Aortic stenosis is characterized both by progressive valve narrowing and the left ventricular
remodeling response that ensues. The only effective treatment is aortic valve replacement …

Objective: To compare the extent and distribution of focal fibrosis by gadolinium contrast-
enhanced magnetic resonance imaging (MRI; delayed hyperenhancement) in severe left …

Objectives: We sought to determine whether the quantitative assessment of myocardial
fibrosis (MF), either by histopathology or by contrast-enhanced magnetic resonance imaging …