Background: With the advances in neuroimaging in amyotrophic lateral sclerosis (ALS), it
has been speculated that multiparametric magnetic resonance imaging (MRI) is capable to …

Timely diagnosis and accurate phenotyping of amyotrophic lateral sclerosis (ALS) is of
paramount importance for the clinical management of patients. Magnetic Resonance …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease whose diagnosis
depends on the presence of combined lower motor neuron (LMN) and upper motor neuron …

The potential of multiparametric quantitative neuroimaging has been extensively discussed
as a diagnostic tool in amyotrophic lateral sclerosis (ALS). In the past, the integration of …

Background Despite significant advances in quantitative neuroimaging, the diagnosis of
ALS remains clinical and MRI-based biomarkers are not currently used to aid the diagnosis …

Background: Amyotrophic Lateral Sclerosis (ALS) is a relentlessly progressive
neurodegenerative condition with limited therapeutic options at present. Survival from …

Background Amyotrophic lateral sclerosis (ALS) is a fatal, rapidly progressive
neurodegenerative disease that mainly affects the motor system. A number of potentially …

A large multiparametric MRI study has been undertaken to evaluate anatomical patterns of
basal ganglia, white matter and cortical grey matter involvement in ALS. Unaffected brain …

Amyotrophic lateral sclerosis (ALS) is an incurable and progressively fatal
neurodegenerative disease that manifests with distinct clinical phenotypes, which are seen …

The prognosis of Amyotrophic Lateral Sclerosis (ALS), a complex and rare disease,
represents a challenging and essential task to better comprehend its progression and …