Background Amyotrophic lateral sclerosis (ALS) a highly heterogeneous neurodegenerative
condition. Accurate diagnostic, monitoring and prognostic biomarkers are urgently needed …

Progressive cerebral degeneration in amyotrophic lateral sclerosis (ALS) remains poorly
understood. Here, three‐dimensional (3D) texture analysis was used to study longitudinal …

Amyotrophic lateral sclerosis (ALS) is now recognised to be a heterogeneous
neurodegenerative syndrome of the motor system and its frontotemporal cortical …

This work evaluates the potential in diagnostic application of a new advanced neuroimaging
method, which delineates the profile of tissue properties along the corticospinal tract (CST) …

Background: There is currently no definite neuroimaging test to detect amyotrophic lateral
sclerosis (ALS), which leads to significant delay in diagnosis, particularly if one takes into …

The description of group-level, genotype-and phenotype-associated imaging traits is
academically important, but the practical demands of clinical neurology centre on the …

Background Multiple sclerosis (MS) is a neurological condition whose symptoms, severity,
and progression over time vary enormously among individuals. Ideally, each person living …

ObjectiveAdvanced neuroimaging techniques may offer the potential to monitor disease
progression in amyotrophic lateral sclerosis (ALS), a neurodegenerative, multisystem …

Background: Increasing neuroimaging studies have revealed gray matter (GM) anomalies of
several brain regions by voxel-based morphometry (VBM) studies in patients with …

MRI and PET studies in ALS have consistently shown patterns of functional and structural
changes considered to be the pathological signature of the disease. The constant advance …