Abstract α 1-Adrenoceptors have been identified and characterized extensively by
functional, radioligand-binding, and molecular biological techniques. Molecular clones have …

We have systematically reviewed the presence, functional responses and regulation of α1‐,
α2‐and β‐adrenoceptors in the bladder, urethra and prostate, with special emphasis on …

α1‐Adrenoceptors are involved in numerous physiological functions, including micturition.
However, the pharmacological profile of the α1‐adrenoceptor subtypes remains …

Abstract α1‐Adrenoceptors are involved in physiological functions such as urinary excretion
and ejaculation in the lower urinary tract (LUT). Several α1 antagonists are clinically used for …

PURPOSE: We provide a comprehensive overview of the role of α1-adrenergic receptors
(α1ARs) as critical mediators of lower urinary tract symptoms (LUTS) and pathophysiology in …

Prostatic α1‐adrenoceptors are known to be involved in the pathophysiology of lower
urinary tract symptoms (LUTS) in patients with benign prostate obstruction (BPO). It is widely …

The cloning of multiple subtypes of both a1-and a2-adrenoceptors has renewed interest in
the therapeutic application of agents interacting with these receptors. Effort has primarily …

This paper reviews the role of α 1-adrenoceptors (ARs) in the aetiology of lower urinary tract
symptoms (LUTS) suggestive of benign prostatic hyperplasia (BPH). α 1-ARs have been …

The external urethral sphincteric mechanism generates forces which seal the urethra and
can be measured as urethral pressure. Resting pressure can be augmented transiently …

The role of alpha 1-adrenoceptors in the mediation of autonomic functions, particularly in the
control of the cardiovascular system, is widely known. It has been shown that alpha 1 …