Autoradiographic localization of α1-adrenoceptors in human prostate: special reference to zonal difference

S Kobayashi, T Demura, K Nonomura, T Koyanagi - The Journal of urology, 1991 - Elsevier
Using autoradiography, localization of al-adrenoceptor in human prostate was examined
with particular reference to zonal difference. Prostatic tissues were obtained from total …

Age-related changes in alpha1-adrenoceptors in rat prostate

N Moriyama, S Kurimoto, Y Nagase, O Inagaki… - Urological …, 1995 - Springer
The age-related changes in the density of alpha 1-adrenoceptors in the dorsolateral lobe of
the rat prostate were evaluated in Wistar rats at 8, 52, and 104 weeks of age.[3 H] YM617, a …

[引用][C] Chapter 12: REC 15/2739 (SB 216469): A Novel Prostate Selective a1-Adrenoceptor Antagonist

R Testa, C Taddei, E Poggesi… - Pharmacology …, 1995 - Chur; Philadelphia: Harwood …

Pharmacological characterization of A‐131701, a novel α1‐adrenoceptor antagonist selective for α1A‐ and α1D‐compared to α1B‐adrenoceptors

AA Hancock, SA Buckner, ME Brune… - Drug Development …, 1998 - Wiley Online Library
New compounds selective for α1A‐adrenoceptors in the prostate may offer enhanced
efficacy for benign prostatic hyperplasia (BPH), with fewer side effects than current …

Evaluation of the pharmacological selectivity profile of α1 adrenoceptor antagonists at prostatic α1 adrenoceptors: binding, functional and in vivo studies

BA Kenny, AM Miller, IJR Williamson… - British journal of …, 1996 - Wiley Online Library
1 The profile of a range of α1 adrenoceptor antagonists was determined in vitro against
cloned human α1A, α1B and α1D adrenoceptors and against noradrenaline‐mediated …

[PDF][PDF] Význam subtypů alfa 1A–adrenoceptorů v terapii symptomů dolních močových cest (LUTS) a benigní hyperplazie prostaty

Z Veselský, P Macek, P Prošvic, P Višňovský, M Förstl - Urologie pro praxi, 2002 - solen.cz
THE SIGNIFICANCE OF THE SUBTYPE ALPHA 1A ADRENORECEPTOR IN THE
THERAPY OF LOW URINARY TRACT SYMPTOMS (LUTS) AND BENIGN PROSTATIC …

α1-Adrenoceptor Subtypes in the Human Carondiovascular and Urogenital Systems

MC Michel, K Taguchi, RS Schäfers, TJ Williams… - Advances in …, 1997 - Elsevier
Publisher Summary α 1-adrenoceptors are most important in the human cardiovascular
system in the vasulature. The subtype (s) mediating vasoconstriction in humans have not yet …

The α1A‐adrenoceptor gene is required for the α1L‐adrenoceptor‐mediated response in isolated preparations of the mouse prostate

KT Gray, JL Short, S Ventura - British journal of pharmacology, 2008 - Wiley Online Library
Background and purpose: This study investigated whether deletion of the α1A‐adrenoceptor
gene influences contractile responses of mouse prostate to noradrenaline. Responses of …

Prostate growth inhibition by subtype‐selective alpha1‐adrenoceptor antagonist naftopidil in benign prostatic hyperplasia

Y Kojima, S Sasaki, N Oda, TA Koshimizu… - The …, 2009 - Wiley Online Library
Abstract BACKGROUND Recently, alpha1‐adrenoceptors (α1‐ARs) have been reported to
play a prominent role in the growth of a variety of cells; however, little is known about …

Clinical significance of α1-adrenoceptor selectivity in the management of benign prostatic hyperplasia

JL Pool, RS Kirby - International urology and nephrology, 2001 - Springer
Alpha 1-adrenoceptor antagonists have beenshown to provide effective relief from
symptomsof benign prostatic hyperplasia (BPH) withattendant improvements in quality of …