Rats bearing cerebrocortical electrodes for recording the electroencephalogram (EEG) were
rendered tolerant to and physically dependent on morphine and subsequently trained to self …

Rats maintained dependence by the self-administration of LAAM or morphine. Following the
substitution of saline for LAAM, REM sleep was not disrupted, and the frequency of lever …

Abstract Adult female Sprague-Dawley rats were prepared with chronic intravenous
cannulas and cortical and muscle electrodes for recording electroencephalograms and …

Abstract Adult female Sprague-Dawley rats were prepared with chronic intravenous
cannulae and cortical and muscle electrodes for recording electro-encephalograms (EEG) …

The discriminative stimulus effects of l-α-acetylmethadol (LAAM), l-α-acetylnormethadol (nor-
LAAM), l-α-acetyldinormethadol (dinor-LAAM), buprenorphine and methadone were …

l-α-Acetyl-N-normethadol (nor-LAAM) and l-α-acetyl-N, N-dinormethadol (dinor-LAAM) are
active metabolites of the opiate l-α-acetylmethadol (LAAM), and they contribute to the …

Morphine post-dependent rats were prepared with chronic cortical EEG and temporalis
muscle EMG electrodes and iv jugular cannulae and permitted to self-administer morphine …

This study characterized discriminative stimulus and other effects of naltrexone in rhesus
monkeys treated daily with the long-acting opioid l-alpha acetylmethadol (LAAM). An initial …

Abstract Adult female Sprague-Dawley rats were prepared with chronic cortical and muscle
electrodes and iv cannulas, made tolerant to and physically dependent on morphine, and …

BALB/c mice were unilaterally implanted with a guide-cannula, the tip of which was
positioned 1 mm above either the lateral hypothalamus (LH) or the mesencephalic central …