Objectives: The aim of the present study was to evaluate whether extracellular volume
fraction (ECV) can reliably inform on the extent of diffuse fibrosis in the simultaneous …

Background Diffuse myocardial fibrosis, and to a lesser extent global myocardial edema, are
important processes in heart disease which are difficult to assess or quantify with …

Objectives: The purpose of this study was to investigate diffuse myocardial fibrosis in
patients with systolic heart failure (SHF) and in patients with heart failure with preserved …

Objectives: In this study we sought to explore the relationship between cardiac magnetic
resonance (CMR) with late gadolinium enhancement (LGE) and histopathological …

The left ventricular (LV) remodeling process associated with significant valvular heart
disease (VHD) is characterized by an increase of myocardial interstitial space with …

Background Diffuse myocardial fibrosis (DMF) is important in cardiovascular disease,
however until recently could only be assessed by invasive biopsy. We hypothesised that …

The current era has seen major advances in myocardial imaging. We are now able to
assess cardiac anatomy, function, tissue composition and disease activity across a wide …

Diffuse myocardial fibrosis (DMF) is an important marker in many cardiac diseases, but its
utility has been limited by the need for biopsy for its assessment. An accurate noninvasive …

Myocardial fibrosis, seen in ischemic and nonischemic cardiomyopathies, is associated with
adverse cardiac outcomes. Noninvasive imaging plays a key role in early identification and …

Objectives: The purpose of this study was to examine the histological correlation of native
myocardial T1 and extracellular volume fraction (ECV) measurement at 3-T for the …