Efficacy of liraglutide for weight loss among patients with type 2 diabetes: the SCALE diabetes randomized clinical trial

MJ Davies, R Bergenstal, B Bode, RF Kushner… - Jama, 2015 - jamanetwork.com
Importance Weight loss of 5% to 10% can improve type 2 diabetes and related
comorbidities. Few safe, effective weight-management drugs are currently available …

Efficacy and safety of liraglutide 3.0 mg in individuals with overweight or obesity and type 2 diabetes treated with basal insulin: the SCALE insulin randomized …

WT Garvey, AL Birkenfeld, D Dicker, G Mingrone… - Diabetes …, 2020 - Am Diabetes Assoc
OBJECTIVE Most individuals with type 2 diabetes also have obesity, and treatment with
some diabetes medications, including insulin, can cause further weight gain. No approved …

A randomized, controlled trial of 3.0 mg of liraglutide in weight management

X Pi-Sunyer, A Astrup, K Fujioka… - … England Journal of …, 2015 - Mass Medical Soc
Background Obesity is a chronic disease with serious health consequences, but weight loss
is difficult to maintain through lifestyle intervention alone. Liraglutide, a glucagon-like …

Efficacy and safety of liraglutide for overweight adult patients with type 1 diabetes and insufficient glycaemic control (Lira-1): a randomised, double-blind, placebo …

TF Dejgaard, CS Frandsen, TS Hansen… - The lancet Diabetes & …, 2016 - thelancet.com
Background The combination of insulin and glucagon-like peptide-1 (GLP-1) receptor
agonist therapy improves glycaemic control, induces weight loss, and reduces insulin dose …

Liraglutide treatment in overweight and obese patients with type 1 diabetes: a 26‐week randomized controlled trial; mechanisms of weight loss

H Ghanim, M Batra, K Green… - Diabetes, Obesity …, 2020 - Wiley Online Library
Aim To investigate the effects of liraglutide treatment on glycaemic control and adipose
tissue metabolism in overweight and obese people with type 1 diabetes (T1DM). Research …

Effects of liraglutide in the treatment of obesity: a randomised, double-blind, placebo-controlled study

A Astrup, S Rössner, L Van Gaal, A Rissanen… - The Lancet, 2009 - thelancet.com
Background The frequency of obesity has risen dramatically in recent years but only few
safe and effective drugs are currently available. We assessed the effect of liraglutide on …

Efficacy and safety of liraglutide added to insulin treatment in type 1 diabetes: the ADJUNCT ONE treat-to-target randomized trial

C Mathieu, B Zinman, JU Hemmingsson, V Woo… - Diabetes …, 2016 - Am Diabetes Assoc
OBJECTIVE To investigate whether liraglutide added to treat-to-target insulin improves
glycemic control and reduces insulin requirements and body weight in subjects with type 1 …

Weight change with liraglutide and comparator therapies: an analysis of seven phase 3 trials from the liraglutide diabetes development programme

K Niswender, X Pi‐Sunyer, J Buse… - Diabetes, Obesity …, 2013 - Wiley Online Library
Aim We investigated the relationship between weight change and related factors in subjects
with type 2 diabetes mellitus (T2DM) treated with liraglutide versus comparator diabetes …

Real‐world clinical effectiveness of liraglutide 3.0 mg for weight management in Canada

S Wharton, A Liu, A Pakseresht, E Nørtoft, CL Haase… - …, 2019 - Wiley Online Library
Objective Real‐world clinical effectiveness of liraglutide 3.0 mg, in combination with diet and
exercise, was investigated 4 and 6 months post initiation. Changes in absolute and percent …

Clinical effectiveness of liraglutide in type 2 diabetes treatment in the real-world setting: a systematic literature review

A Ostawal, E Mocevic, N Kragh, W Xu - Diabetes Therapy, 2016 - Springer
Introduction In clinical trials, liraglutide has proven to be an effective drug for the treatment of
type 2 diabetes mellitus (T2DM). The real-world effectiveness of liraglutide has been …