Effects of acute and continuous administration of morphine on the cyclic AMP response induced by norepinephrine in rat brain slices

CS Mehta, SJ Strada - Life sciences, 1994 - Elsevier
Pre-incubated cortical brain slices from adult male Sprague Dawley rats when challenged
by exogenous norepinephrine (NE) exhibited a dose-dependent increase in the level of …

Involvement of brain cyclic AMP in the acute and chronic effects of morphine in the rat

KSS Salles, BK Colasanti, CR Craig, JA Thomas - Pharmacology, 1978 - karger.com
Incubation of cerebral cortical slices of rat brain with 3H-adenosine in the presence of
varying concentrations of morphine in vitro resulted in a dose-related increase in 3H-cAMP …

Effect of morphine on catecholamine‐stimulated cyclic AMP production in cortex slices from rats and mice

P Slater, C Blundell - Journal of neuroscience research, 1981 - Wiley Online Library
Morphine (10 μM) blocked noradrenaline‐stimulated cyclic AMP production in slices of
cerebral cortex from normal rats but not in slices from rats pretreated with 6 …

Possible role of cyclic AMP and dopamine in morphine tolerance and physical dependence

CS Mehta, WE Johnson - Life Sciences, 1975 - Elsevier
In chronically morphinized rats undergoing naloxone induced withdrawal the cerebellar
Cyclic 3′, 5′ adenosine monophosphate (Cyclic AMP) was significantly higher than the …

Effect of cyclic nucleotides and phosphodiesterase inhibition on morphine tolerance and physical dependence

IK Ho, HH Loh, HN Bhargava, EL Way - Life Sciences, 1975 - Elsevier
The effects of cyclic nucleotides and theophylline were assessed in mice rendered tolerant
to and physically dependent on morphine by the pellet implantation procedure. Tolerance …

Extraneuronal noradrenaline in the prefrontal cortex of morphine-dependent rats: tolerance and withdrawal mechanisms.

ZL Rossetti, G Longu, G Mercuro, GL Gessa - Brain research, 1993 - europepmc.org
The changes in extracellular concentrations of noradrenaline (NA) in the prefrontal cortex of
morphine-dependent rats were studied by microdialysis following an acute morphine …

Elevation of brain dopamine during naloxone-precipitated withdrawal in morphine-dependent mice and rats

ET Iwamoto, IK Ho, EL Way - Journal of Pharmacology and Experimental …, 1973 - ASPET
Mice were rendered dependent on morphine by the subcutaneous pellet implantation
technique. After three days, the pellet was removed and six hours later, withdrawal jumping …

Extraneuronal noradrenaline in the prefrontal cortex of morphine-dependent rats: tolerance and withdrawal mechanis

ZL Rossetio, G Longu, G Mercuro, GL Gessa - Brain Research, 1993 - Elsevier
The changes in extracellular concentrations of noradrenaline (NA) in the prefrontal cortex of
morphine-dependent rats were studied by microdialysis following an acute morphine …

Inhibition of morphine tolerance and dependence by diazepam and its relation to cyclic AMP levels in discrete rat brain regions and spinal cord

MJ Sheu, P Sribanditmongkol, DN Santosa… - Brain research, 1995 - Elsevier
Diazepam inhibits morphine tolerance and dependence and reverses a decrease in the met-
enkephalin level in brain induced by morphine. In this study, we investigated whether …

Effect of narcotic analgesics on plasma cyclic AMP levels in male mice

T Muraki, T Nakadate, Y Tokunaga, R Kato - Neuropharmacology, 1979 - Elsevier
Systemic administration of morphine, as well as pethidine and pentazocine, increased
plasma cyclic AMP levels in male mice. Intracerebroventricular administration of morphine …