[PDF][PDF] Construction of New Simian/Human Immunodeficiency Chimeric Viruses (SHIVs) towards a Better Animal Model for HIV-1 Infection in Humans
H Akiyama - 2004 - repository.kulib.kyoto-u.ac.jp
んでいない. その原因の一つとして, HIV-1 がヒト以外にはチンパンジーといった限られた動物にしか
感染せず, アカゲザル等の医学実験用動物を用いて実験的解析が行えないことによる HIV-1 …
感染せず, アカゲザル等の医学実験用動物を用いて実験的解析が行えないことによる HIV-1 …
[PDF][PDF] Study of AIDS pathogenesis using infectious molecular clones of simian/human immunodeficiency chimeric viruses.
IL Kozyrev - 2001 - repository.kulib.kyoto-u.ac.jp
ヒト免疫不全ウイルス 1 型 (HIV-1) は, 後天性免疫不全症候群 (AIDS) の原因ウイルスである. HIV-
1 の病原性の解明や, ワクチン･ 治療薬の開発のためには個体レベルで実験的に取り扱える動物 …
1 の病原性の解明や, ワクチン･ 治療薬の開発のためには個体レベルで実験的に取り扱える動物 …
4. HIV の病原性とエイズ弱毒生ワクチン開発—サルを用いたモデル—
速水正憲， 堀内励生 - ウイルス, 2004 - jstage.jst.go.jp
抄録 HIV のワクチン開発研究は最新のウイルス学・免疫学の基礎知見に基づいて,
様々な創意工夫により取り組まれている. ただし有効なものの実用化には悲観的な空気が強い …
様々な創意工夫により取り組まれている. ただし有効なものの実用化には悲観的な空気が強い …
[PDF][PDF] Protection of Macaques Vaccinated with Gene-Deleted HIV-1/SIVmac Chimeric Viruses (SHIVs) Having HIV-1 Env against a Gene-Intact SHIV: a Potential of …
M Ui - 2000 - repository.kulib.kyoto-u.ac.jp
後天性免疫不全症候群 (ェイズ) の原因ウイルスであるヒト免疫不全ウイルス 1 型 (HIV-1)
は全世界で流行しており, その蔓延を阻止するためには安価で有効なワクチンの開発が急務である …
は全世界で流行しており, その蔓延を阻止するためには安価で有効なワクチンの開発が急務である …
Using SHIVs to develop an anti-HIV-1 live-attenuated vaccine
T Kuwata, T Miura, M Hayami - TRENDS in Microbiology, 2001 - cell.com
The use of chimeric simian and human immunodeficiency viruses (SHIVs) that encode HIV-1
Env and are infectious to macaques has made it possible to analyze the pathogenicity of HIV …
Env and are infectious to macaques has made it possible to analyze the pathogenicity of HIV …
SIV/HIV-1 chimeric viruses having HIV-1 env gene: a new animal model and a candidate for attenuated live vaccine.
M HAYAMI, T IGARASHI - Leukemia (08876924), 1997 - search.ebscohost.com
In order to generate an HIV-1, which is infectious to and induces AIDS-like disease in
monkeys, tin SIVmac/HIV-1 chimeric virus, designated NM-3rN, which was replication …
monkeys, tin SIVmac/HIV-1 chimeric virus, designated NM-3rN, which was replication …
Infection of baboons with a simian immunodeficiency virus/HIV-1 chimeric virus constructed with an HIV-1 Thai subtype E envelope
JM Klinger, S Himathongkham, H Legg, PA Luciw… - Aids, 1998 - journals.lww.com
Objective: To construct an infectious chimeric simian immunodeficiency virus/HIV-1 (SHIV)
with the envelope of a Thai subtype E HIV-1 strain for use in a non-human primate model …
with the envelope of a Thai subtype E HIV-1 strain for use in a non-human primate model …
Gene-mutated HIV-1/SIV chimeric viruses as AIDS live attenuated vaccines for potential human use
M Hayami, T Igarashi, T Kuwata, M Ui, T Haga, Y Ami… - Leukemia, 1999 - nature.com
To develop an AIDS vaccine for human use as well as a suitable animal model for AIDS
research, we constructed a series of HIV-1/SIVmac chimeric viruses (SHIVs). We …
research, we constructed a series of HIV-1/SIVmac chimeric viruses (SHIVs). We …
Characterization of simian and human immunodeficiency chimeric viruses re-isolated from vaccinated macaque monkeys after challenge infection
TB Kwofie, T Miura, K Ibuki, Y Enose, H Suzuki, M Ui… - Archives of …, 2002 - Springer
Monkeys that have been vaccinated with nef-deleted SHIVs were either fully or partially
protected against challenge with acute pathogenic SHIV-89.6 P. Viruses isolated from these …
protected against challenge with acute pathogenic SHIV-89.6 P. Viruses isolated from these …
Studies on virulence of HIV and development of non-virulent live AIDS vaccine using monkeys
M Hayami, R Horiuchi - Uirusu, 2004 - europepmc.org
A great effort for developing AIDS vaccine has been carried out in the world, designed by
various new ideas based on basic research information obtained in recent virology and …
various new ideas based on basic research information obtained in recent virology and …