Primary lateral sclerosis (PLS) is an extremely rare central nervous system degenerative
disorder characterized by slowly progressive upper motor neuron loss leading to severe …

Primary lateral sclerosis (PLS) is a rare neurodegenerative disorder at the upper motor
neurone extreme of the spectrum of motor neurone disease. The diagnosis is clinical and …

Advances in clinical care and recent research achievements: Primary lateral sclerosis (PLS)
has traditionally been regarded as a pure upper motor neuron condition, a view perpetuated …

Primary lateral sclerosis (PLS) is a condition that most neurologists will never personally
diagnose. For the estimated several thousand people living with PLS globally, while it may …

Primary lateral sclerosis (PLS) is a disorder of progressive upper motor neuron dysfunction,
in the absence of clinical signs of lower motor neuron involvement or family history …

Like motor neuron diseases (MNDs) refer to a constellation of primarily sporadic
neurodegenerative diseases characterized by a progressive loss of upper and/or lower …

Primary lateral sclerosis (PLS) is a neurodegenerative disorder of the adult motor system.
Characterised by a slowly progressive upper motor neuron syndrome, the diagnosis is …

Introduction Primary lateral sclerosis (PLS) is a rare, adult-onset and slowly progressive
motor neuron disorder whose clinical core is characterized by upper motor neuron (UMN) …

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that results in
progressive loss of bulbar and limb function. Patients typically die from respiratory failure …

Abstract Primary Lateral Sclerosis (PLS) is an uncommon motor neuron disorder. Despite
the well-recognisable constellation of clinical manifestations, the initial diagnosis can be …