Alzheimer's disease variant portal: a Catalog of genetic findings for Alzheimer's disease
Background: Recent Alzheimer's disease (AD) genetics findings from genome-wide
association studies (GWAS) span progressively larger and more diverse populations and …
association studies (GWAS) span progressively larger and more diverse populations and …
NIAGADS Alzheimer's GenomicsDB: A resource for exploring Alzheimer's disease genetic and genomic knowledge
E Greenfest‐Allen, O Valladares… - Alzheimer's & …, 2024 - Wiley Online Library
Abstract INTRODUCTION The National Institute on Aging Genetics of Alzheimer's Disease
Data Storage Site Alzheimer's Genomics Database (GenomicsDB) is a public knowledge …
Data Storage Site Alzheimer's Genomics Database (GenomicsDB) is a public knowledge …
Large‐scale sequencing studies expand the known genetic architecture of Alzheimer's disease
Introduction Genes implicated by genome‐wide association studies and family‐based
studies of Alzheimer's disease (AD) are largely discordant. We hypothesized that genes …
studies of Alzheimer's disease (AD) are largely discordant. We hypothesized that genes …
Interpretation of 10 years of Alzheimer's disease genetic findings in the perspective of statistical heterogeneity
S Gao, T Wang, Z Han, Y Hu, P Zhu… - Briefings in …, 2024 - academic.oup.com
Common genetic variants and susceptibility loci associated with Alzheimer's disease (AD)
have been discovered through large-scale genome-wide association studies (GWAS) …
have been discovered through large-scale genome-wide association studies (GWAS) …
Key variants via the Alzheimer's Disease Sequencing Project whole genome sequence data
INTRODUCTION Genome‐wide association studies (GWAS) have identified loci associated
with Alzheimer's disease (AD) but did not identify specific causal genes or variants within …
with Alzheimer's disease (AD) but did not identify specific causal genes or variants within …
The complex genetic architecture of Alzheimer's disease: novel insights and future directions
SJ Andrews, AE Renton, B Fulton-Howard… - …, 2023 - thelancet.com
Background Alzheimer's disease (AD) is a complex multifactorial neurodegenerative
disorder and the most common form of dementia. AD is highly heritable, with heritability …
disorder and the most common form of dementia. AD is highly heritable, with heritability …
Genomic variants, genes, and pathways of Alzheimer's disease: An overview
AC Naj, GD Schellenberg… - American Journal of …, 2017 - Wiley Online Library
Alzheimer's disease (AD)(MIM: 104300) is a highly heritable disease with great complexity
in its genetic contributors, and represents the most common form of dementia. With the …
in its genetic contributors, and represents the most common form of dementia. With the …
An overview of genome-wide association studies in Alzheimer's disease
L Shen, J Jia - Neuroscience bulletin, 2016 - Springer
Genome-wide association studies (GWASs) have revealed a plethora of putative
susceptibility genes for Alzheimer's disease (AD). With the sole exception of the APOE gene …
susceptibility genes for Alzheimer's disease (AD). With the sole exception of the APOE gene …
Genetic Loci Associated With Alzheimer's Disease
C Reitz - Future neurology, 2014 - Taylor & Francis
EVALUATION OF: Lambert JC, Ibrahim-Verbaas CA, Harold D et al. Meta-analysis of 74,046
individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nat. Genet. 45 (12) …
individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nat. Genet. 45 (12) …
Shared genetic risk loci between Alzheimer's disease and related dementias, Parkinson's disease, and amyotrophic lateral sclerosis
Background Genome-wide association studies (GWAS) have indicated moderate genetic
overlap between Alzheimer's disease (AD) and related dementias (ADRD), Parkinson's …
overlap between Alzheimer's disease (AD) and related dementias (ADRD), Parkinson's …