Background This study was performed to assess changes in diffusion tensor imaging (DTI)
over time in patients with amyotrophic lateral sclerosis (ALS). Methods We performed DTI in …

Objective Using magnetic resonance (MR) high angular resolution diffusion imaging
(HARDI), we aimed at revealing possible microstructural alterations in the early stage of …

Background After the demonstration of a corticoefferent propagation pattern in amyotrophic
lateral sclerosis (ALS) by neuropathological studies, this concept has been used for in vivo …

Numerous neuroimaging studies in amyotrophic lateral sclerosis (ALS) have reported links
between structural changes and clinical data; however phenotypic and disease course …

Neurodegenerative process in amyotrophic lateral sclerosis (ALS) has been proven to
involve several cortical and subcortical brain regions within and beyond motor areas …

Pathological and imaging data indicate that amyotrophic lateral sclerosis (ALS) is a
multisystem disease involving several cerebral cortical areas. Advanced quantitative …

Objective Advanced neuroimaging techniques may offer the potential to monitor disease
spreading in amyotrophic lateral sclerosis (ALS). We aim to investigate brain functional and …

Objective Damage to the cerebral tissue structural connectivity associated with amyotrophic
lateral sclerosis (ALS), which extends beyond the motor pathways, can be visualised by …

In this study, we investigated whether diffusion tensor MRI (DTI) could detect progressive
corticospinal tract degeneration in amyotrophic lateral sclerosis (ALS) and whether changes …

Voxel‐based analyses (VBA) are increasingly being used to detect white matter
abnormalities with diffusion tensor imaging (DTI) in different types of pathologies. However …