In amyotrophic lateral sclerosis (ALS), diffusion weighted magnetic resonance imaging (DW-
MRI) has produced mounting evidence of a widespread white matter (WM) damage within …

Introduction The brainstem is an important component in the pathology of amyotrophic
lateral sclerosis (ALS). Although neuroimaging studies have shown multiple structural …

Amyotrophic lateral sclerosis (ALS) is a fatal motor neuron disease for which a precise
cause has not yet been identified. Standard CT or MRI evaluation does not demonstrate …

Amyotrophic lateral sclerosis (ALS) is a motor neuron disease characterized by progressive
degeneration of upper motor neurons (UMN) and lower motor neurons (LMN). While LMN …

Introduction. Despite the rapid development of neuroimaging techniques, the diagnosis of
amyotrophic lateral sclerosis (ALS) remains a significant challenge. Magnetic resonance …

ObjectiveAdvanced neuroimaging techniques may offer the potential to monitor disease
progression in amyotrophic lateral sclerosis (ALS), a neurodegenerative, multisystem …

Objective To construct a clinical diagnostic biomarker using state-of-the-art microstructural
MRI in the motor cortex of people with amyotrophic lateral sclerosis (ALS). Methods Clinical …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease, characterized by
progressive loss of motor function. While the pathogenesis of ALS remains largely unknown …

Amyotrophic lateral sclerosis (ALS) is a predominantly clinical and electromyographic
diagnosis. Conventional MRI reveals atrophy of the motor system, particularly the pyramidal …

ABSTRACT Background and Purpose: Diffusion tensor imaging (DTI) was used as a
noninvasive method to evaluate the anatomy of the corticospinal tract (CST) and the pattern …