Serum albumin-alginate coated microspheres: role of the inner gel in binding and release of the KRFK peptide

M Callewaert, JM Millot, J Lesage… - International Journal of …, 2009 - Elsevier
In continuation with our previous study using fluorescein-isothiocyanate (FITC)–Lys-Arg-Phe-
Lys (KRFK) peptide, the aim of this work was to study the interaction of the unlabelled KRFK …

Coating alginate microspheres with a serum albumin-alginate membrane: application to the encapsulation of a peptide

R Hurteaux, F Edwards-Lévy, D Laurent-Maquin… - European Journal of …, 2005 - Elsevier
Calcium alginate gel microspheres coated with a human serum albumin (HSA)-alginate
membrane were prepared adapting a transacylation method previously applied to large …

Protein immobilization in crosslinked alginate microparticles

G Coppi, V Iannuccelli, E Leo… - Journal of …, 2002 - Taylor & Francis
Oral administration of peptide and protein drugs requires their protection from the acidic and
enzymatic degradation in the gastro-intestinal environment and their targeting to the …

Extended release of high pI proteins from alginate microspheres via a novel encapsulation technique

LA Wells, H Sheardown - European journal of pharmaceutics and …, 2007 - Elsevier
Alginate has potential as a matrix for controlled delivery of protein-based drugs that require
site-specific long-term delivery. In the current work albumin, lysozyme and chymotrypsin …

Emulsan, a tailorable biopolymer for controlled release

GR Castro, B Panilaitis, DL Kaplan - Bioresource technology, 2008 - Elsevier
Microsphere hydrogels made with emulsan–alginate were used as carrier for the
microencapsulation of blue dextran in order to study the effect of emulsan on the alginate …

An investigation of the factors controlling the adsorption of protein antigens to anionic PLG microparticles

J Chesko, J Kazzaz, M Ugozzoli, DT O'Hagan… - Journal of …, 2005 - Elsevier
This work examines physico-chemical properties influencing protein adsorption to anionic
PLG microparticles and demonstrates the ability to bind and release vaccine antigens over a …

Preparation and characterization of alginate microspheres containing a model antigen

D Lemoine, F Wauters, S Bouchend'Homme… - International journal of …, 1998 - Elsevier
The goal of this study was to evaluate the technological feasibility of delivering antigen using
alginate microspheres. The microspheres were prepared by an emulsification technique and …

Microencapsulation of lipophilic drugs in chitosan-coated alginate microspheres

AJ Ribeiro, RJ Neufeld, P Arnaud… - International journal of …, 1999 - Elsevier
Chitosan-coated alginate microspheres containing a lipophilic marker dissolved in an edible
oil, were prepared by emulsification/internal gelation and the potential use as an oral …

Protein loss by the microencapsulation of an enzyme (lactase) in alginate beads

A Dashevsky - International journal of Pharmaceutics, 1998 - Elsevier
Alginate gel beads are used in many applications as matrices for release or immobilisation.
The problems of enzyme stability and low entrapment efficiency by this microencapsulation …

Preparation and characterization of BSA-loaded alginate microspheres

M Çetin, I Vural, Y Çapan… - Fabad Journal of …, 2007 - search.proquest.com
This study describes the preparation and characterization of a model protein (bovine serum
albumin; BSA)-loaded alginate microspheres. BSA was encapsulated within alginate …