Cholinergic dysfunction in diseases with Lewy bodies

P Tiraboschi, LA Hansen, M Alford, MN Sabbagh… - Neurology, 2000 - AAN Enterprises
Objective: To evaluate cholinergic activity in diseases with Lewy bodies (LB; LB variant of
AD [LBV], diffuse LB disease [DLBD], and Parkinson's disease [PD]) to determine if 1) AD …

Association of cortical hyperexcitability and cognitive impairment in patients with amyotrophic lateral sclerosis

M Higashihara, N Pavey, M van den Bos, P Menon… - Neurology, 2021 - AAN Enterprises
Objective To determine whether cortical hyperexcitability was more prominent in cognitively
impaired patients with amyotrophic lateral sclerosis (ALS). Methods Threshold tracking …

Activation of basal ganglia loops in idiopathic Parkinson's disease: a PET study

A Thiel, R Hilker, J Kessler, B Habedank… - Journal of neural …, 2003 - Springer
Patients with idiopathic Parkinson's syndrome (IPS) show dysexecutive deficits which are
not related to dementia. We investigated whether these deficits may be caused by a …

Differentiating between visual hallucination-free dementia with Lewy bodies and corticobasal syndrome on the basis of neuropsychology and perfusion single-photon …

MR Misch, S Mitchell, PL Francis, K Sherborn… - Alzheimer's Research & …, 2014 - Springer
Abstract Introduction Dementia with Lewy bodies (DLB) and Corticobasal Syndrome (CBS)
are atypical parkinsonian disorders with fronto-subcortical and posterior cognitive …

Brain volume changes in Parkinson's disease and their relationship with cognitive and behavioural abnormalities

R Biundo, P Formento-Dojot, S Facchini… - Journal of the …, 2011 - Elsevier
Cognitive and behavioral abnormalities are frequent in Parkinson's disease (PD) but their
anatomical correlates are still uncertain. We assessed a cohort of 59 PD patients with and …

Can we predict development of impulsive–compulsive behaviours in Parkinson's disease?

L Ricciardi, C Lambert, R De Micco… - Journal of Neurology …, 2018 - jnnp.bmj.com
Objective To determine clinical and structural imaging predictors of impulsive–compulsive
behaviour (ICB) in de novo Parkinson's disease (PD). Methods From a cohort of 1116 …

Revisiting the pathoanatomy of pseudobulbar affect: mechanisms beyond corticobulbar dysfunction

P Bede, E Finegan - Amyotrophic Lateral Sclerosis and …, 2018 - Taylor & Francis
Pathological crying and laughing (PCL) is one of the most distressing neurological
symptoms, which is prevalent in a range of conditions from multiple sclerosis to ALS. The …

Somatoform and dissociative disorders

CR Cloninger, M Dokucu - The medical basis of psychiatry, 2008 - Springer
abstract Most patients consulting physicians have a mixture of physical and mental
complaints that require careful differential diagnosis. A somatoform disorder is diagnosed …

Corticostriatal beta oscillation changes associated with cognitive function in Parkinson's disease

DL Paulo, H Qian, D Subramanian, GW Johnson… - Brain, 2023 - academic.oup.com
Cognitive impairment is the most frequent non-motor symptom in Parkinson's disease and is
associated with deficits in a number of cognitive functions including working memory …

Neuropathology and emerging biomarkers in corticobasal syndrome

S Koga, KA Josephs, I Aiba, M Yoshida… - Journal of Neurology …, 2022 - jnnp.bmj.com
Corticobasal syndrome (CBS) is a clinical syndrome characterised by progressive
asymmetric limb rigidity and apraxia with dystonia, myoclonus, cortical sensory loss and …