Fentanyl rose to prominence as an alternative analgesic to morphine nearly 50 years ago;
today, fentanyl has re-emerged as a dangerous recreational substance. The increased …

Illicitly manufactured fentanyl is driving the current opioid crisis, and various fentanyl
analogs are appearing in recreational drug markets worldwide. To assess the potential …

The United States is experiencing an epidemic of opioid overdose deaths. Many of the
recent fatalities are associated with illicitly manufactured fentanyl, which is being added to …

Fentanyl and its analogs have been mainstays for the treatment of severe to moderate pain
for many years. In this review, we outline the structural and corresponding synthetic …

Fentanyl is a fully synthetic opioid with analgesic and anesthetic properties. It has become a
primary driver of the deadliest opioid crisis in the United States and elsewhere …

Up to now, little is known about the metabolic pathways of new fentanyl analogs that have
recently emerged on the drug markets worldwide with high potential for producing addiction …

Opioids are widely misused and account for almost half of overdose deaths in the United
States. The cost in terms of lives, health care, and lost productivity is significant and has …

With its remarkable analgesic potency, often 50 to 100 times greater than morphine, fentanyl
presents a valuable tool in addressing acute and chronic pain, as well as in providing …

Fentanyl is a key therapeutic, used in anaesthesia and pain management. It is also
increasingly used illicitly and is responsible for a large and growing number of opioid …

Fentanyl derivatives (FENS) belongs to the class of Novel Synthetic Opioids that emerged in
the illegal drug market of New Psychoactive Substances (NPS). These substances have …