Background: Aortic stenosis is accompanied by progressive left ventricular hypertrophy and
fibrosis. We investigated the natural history of these processes in asymptomatic patients and …

Aortic stenosis (AS) is characterized by progressive narrowing of the valve and the
hypertrophic response of the left ventricle (LV) that ensues (1). Although initially adaptive …

Background—In this prospective follow-up study, the effect of myocardial fibrosis on
myocardial performance in symptomatic severe aortic stenosis was investigated, and the …

Background Cardiovascular magnetic resonance (CMR) is the gold standard non-invasive
method for determining left ventricular (LV) mass and volume but has not been used …

Background—Recent works using echocardiography suggested that low gradient (LG), low
flow (LF) aortic stenosis (AS) has more pronounced left ventricular (LV) concentric …

Background: Left ventricular (LV) hypertrophy, a key process in human cardiac disease,
results from cellular (hypertrophy) and extracellular matrix expansion (interstitial fibrosis) …

Aortic stenosis is characterized both by progressive valve narrowing and the left ventricular
remodeling response that ensues. The only effective treatment is aortic valve replacement …

Background The optimal timing of aortic valve replacement in asymptomatic patients with
aortic stenosis is uncertain. Replacement fibrosis, as assessed by midwall (nonischemic) …

Objectives: This prospective cohort study in patients with aortic stenosis (AS) aimed to
identify surrogates of myocardial fibrosis that are easy to derive in clinical practice, allow the …

Objectives: The goal of this study was to assess the prognostic significance of midwall and
infarct patterns of late gadolinium enhancement (LGE) in aortic stenosis. Background …