[PDF][PDF] Pharmacokinetic analysis of enterohepatic circulation of buprenorphine and its active metabolite, norbuprenorphine, in rats.
M Ohtani, H Kotaki, K Uchino, Y Sawada… - Drug metabolism and …, 1994 - Citeseer
The pharm. cokinedc charactrlstlcs of buprenorphine(BN) and its actlv#{149} metabOIfte, no,
buprenorphln(NBN), was Investigated using rats. Thi elimination half-life (t112), total body …
buprenorphln(NBN), was Investigated using rats. Thi elimination half-life (t112), total body …
Development and validation of a gas chromatography–mass spectrometry method for the simultaneous determination of buprenorphine, flunitrazepam and their …
S Pirnay, S Bouchonnet, F Hervé, D Libong… - … of Chromatography B, 2004 - Elsevier
Buprenorphine (BUP), a synthetic opioid analgesic, is frequently abused alone, and in
association with benzodiazepines. Fatalities involving buprenorphine alone seem very …
association with benzodiazepines. Fatalities involving buprenorphine alone seem very …
Disposition in the rat of buprenorphine administered parenterally and as a subcutaneous implant
RB Pontani, NL Vadlamani, AL Misra - Xenobiotica, 1985 - Taylor & Francis
1. Disposition of [15, 16 (n)-3H] buprenorphine in the rat has been investigated after a single
0· 2 mg/kg iv bolus dose and continuous administration via a sc implantable long-acting …
0· 2 mg/kg iv bolus dose and continuous administration via a sc implantable long-acting …
Pharmacokinetic comparison of sustained-release and standard buprenorphine in mice
TS Clark, DD Clark, RF Hoyt - Journal of the American …, 2014 - ingentaconnect.com
Effective pain medication is important for animal stewardship and valid research results. We
compared the pharmacokinetic assessments of standard, immediate-release buprenorphine …
compared the pharmacokinetic assessments of standard, immediate-release buprenorphine …
Determination of buprenorphine by high-performance liquid chromatography with fluorescence detection: application to human and rabbit pharmacokinetic studies
ST Ho, JJ Wang, W Ho, OYP Hu - Journal of Chromatography B …, 1991 - Elsevier
A rapid, sensitive, precise and accurate high-performance liquid chromatographic assay
with fluorescence detection was developed for the determination of buprenorphine in …
with fluorescence detection was developed for the determination of buprenorphine in …
[引用][C] The mass balance of buprenorphine in humans
ET Everhart, P Cheung, J Mendelson… - Clinical …, 1999 - Wiley Online Library
The mass balance of buprenorphine in humans Page 1 CLINICAL PHARMACOLOGY &
THERAPEUTICS 1 52 American Society for Clinical Pharmacology and Therapeutics …
THERAPEUTICS 1 52 American Society for Clinical Pharmacology and Therapeutics …
Analysis of buprenorphine in rat plasma using a solid-phase extraction technique and high-performance liquid chromatography with electrochemical detection
A Salem, TL Pierce, W Hope - Journal of pharmacological and toxicological …, 1997 - Elsevier
A solid-phase extraction method and sensitive reversed phase high-performance liquid
chromatography analysis with electrochemical detection of buprenorphine and its …
chromatography analysis with electrochemical detection of buprenorphine and its …
Clinical pharmacology of buprenorphine: ceiling effects at high doses
SL Walsh, KL Preston, ML Stitzer… - Clinical …, 1994 - Wiley Online Library
Objective The purpose of this study was to characterize the acute effects of buprenorphine,
an opioid partial (μ‐agonist, across a wide range of doses in comparison to methadone …
an opioid partial (μ‐agonist, across a wide range of doses in comparison to methadone …