Objective The aim of this investigation was to characterize the pharmacokinetics of
buprenorphine following administration of an intravenous (iv) infusion. To date, the …

Effective management of pain in animals is of critical importance but options are limited for
treating acute pain in dogs on an outpatient basis. The objective of this study was to …

■ MATERIALS AND METHODS The Purdue Animal Care and Use Committee approved
this study. Eight healthy 2-yearold purpose-bred mixed-breed research dogs weighing …

Buprenorphine is used during pregnancy for the treatment of opioid use disorder. Limited
data exist on the central nervous system (CNS) permeation and distribution, and on the fetal …

Buprenorphine is a partial μ agonist opioid used for analgesia in dogs. An extended‐release
formulation (ER‐buprenorphine) has been shown to provide effective analgesia for 72 hr in …

The purpose of the present study of buprenorphine is to add information about the
correlation between various animal models and nasal bioavailabilities in man. PEG 300 was …

Buprenorphine is a long-acting opiate with a high therapeutic index. The authors review the
pharmacology, toxicity, analgesic effects and delivery of buprenorphine for use in laboratory …

Pain management in rabbits can be difficult because they are adept at hiding pain and can
be stressed by handling and restraint for injection. The use of opioid analgesics with …

Background: Buprenorphine is used as an analgesic for postoperative and chronic pain. The
usual sublingual dose is 0.2 to 0.8 mg, and the usual parenteral dose is 0.3 mg for acute …