The objective of this study was to assess the relationship between imaging surrogates for
diffuse fibrosis and myocardial dysfunction. Thirty-six New Zealand white rabbits were …

Purpose To pathologically verify the correlation between native T1 mapping, postcontrast T1
mapping, and extracellular volume fraction (ECV) and myocardial diffuse fibrosis, as …

Background Diffuse myocardial interstitial fibrosis (DMIF) is a key factor for heart failure (HF)
in diabetic cardiomyopathy. MRI T1‐mapping technique can quantitatively evaluate DMIF …

Objective To detect diffuse myocardial fibrosis in different severity levels of left ventricular
diastolic dysfunction (DD) in spontaneous type 2 diabetes mellitus (T2DM) rhesus monkeys …

Background—Diabetic patients have increased interstitial myocardial fibrosis on histological
examination. Magnetic resonance imaging (MRI) T1 mapping is a previously validated …

Type 2 diabetes mellitus (T2DM) is associated with a high prevalence of diastolic
dysfunction and congestive heart failure. A potential contributing factor is the accelerated …

Purpose To quantitatively evaluate the dynamic changes of extracellular volume (ECV) and
native T1 in hypertensive swine over time using histologic findings as standard of reference …

Background—The concentration of gadopentetate dimeglumine in myocardium and blood
can be assessed from T1 measurements and can be used to calculate the extracellular …

Objectives We aimed to evaluate myocardial fibrosis using cardiac magnetic resonance
(CMR) T1 mapping in type 2 diabetes mellitus (T2DM) patients and investigate the …

Aims To characterize changes in the myocardium in subjects with prediabetes, diabetes,
and healthy controls with preserved left ventricular ejection fraction (LVEF) by using cardiac …