Genetic risk factors for Alzheimer's disease in racial/ethnic minority populations in the US: a scoping review

L Rubin, LA Ingram, NV Resciniti… - Frontiers in Public …, 2021 - frontiersin.org
Objectives: As the United States (US) population rapidly ages, the incidence of Alzheimer's
Disease and Related Dementias (ADRDs) is rising, with racial/ethnic minorities affected at …

Asian Cohort for Alzheimer's Disease (ACAD) pilot study on genetic and non‐genetic risk factors for Alzheimer's disease among Asian Americans and Canadians

PC Ho, WH Yu, BL Tee, WP Lee, C Li… - Alzheimer's & …, 2024 - Wiley Online Library
INTRODUCTION Clinical research in Alzheimer's disease (AD) lacks cohort diversity despite
being a global health crisis. The Asian Cohort for Alzheimer's Disease (ACAD) was formed …

Differences in the frequency of Alzheimer's disease‐associated genomic variations in populations of different races

P Huang, SW Hsieh, YH Chang… - Geriatrics & …, 2017 - Wiley Online Library
Aim The general genetic background is important when studying major common diseases,
such as Alzheimer's disease (AD). Determining the underlying genetic factors in populations …

Genetics of Alzheimer's disease in the African American population

MW Logue, S Dasgupta, LA Farrer - Journal of Clinical Medicine, 2023 - mdpi.com
Black/African American (AA) individuals have a higher risk of Alzheimer's disease (AD) than
White non-Hispanic persons of European ancestry (EUR) for reasons that may include …

Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities

A Nazarian, AI Yashin, AM Kulminski - Alzheimer's research & therapy, 2019 - Springer
Background Alzheimer's disease (AD) is the most common cause of dementia in the elderly
and the sixth leading cause of death in the United States. AD is mainly considered a …

The Add Health Parent Study: A Biosocial Resource for the Study of Multigenerational Racial/Ethnic Disparities in Alzheimer's Disease and Alzheimer's Disease …

KM Perreira, VJ Hotz, NN Duke, AE Aiello… - Journal of Alzheimer's … - content.iospress.com
Background: Alzheimer's disease and Alzheimer's disease related dementias (AD/ADRD)
have increased in prevalence. Objective: This article describes the Add Health Parent Study …

Offspring study of racial and ethnic disparities in Alzheimer's disease: objectives and design

J Manly, MA Rentería, JF Avila-Rieger, IC Turney… - 2020 - osf.io
Abstract The Offspring Study of Racial and Ethnic Disparities in Alzheimer's Disease began
in 2017 to identify biological and sociocultural mechanisms of disparities in cognitive …

The power of representation: Statistical analysis of diversity in US Alzheimer's disease genetics data

D Xue, EE Blue, MP Conomos… - Alzheimer's & Dementia …, 2024 - Wiley Online Library
INTRODUCTION Alzheimer's disease (AD) is a complex disease influenced by genetics and
environment. More than 75 susceptibility loci have been linked to late‐onset AD, but most of …

Novel Alzheimer disease risk loci and pathways in African American individuals using the African genome resources panel: a meta-analysis

BW Kunkle, M Schmidt, HU Klein, AC Naj… - JAMA …, 2021 - jamanetwork.com
Importance Compared with non-Hispanic White individuals, African American individuals
from the same community are approximately twice as likely to develop Alzheimer disease …

Admixture mapping reveals the association between Native American ancestry at 3q13. 11 and reduced risk of Alzheimer's disease in Caribbean Hispanics

ARVR Horimoto, D Xue, TA Thornton… - Alzheimer's Research & …, 2021 - Springer
Background Genetic studies have primarily been conducted in European ancestry
populations, identifying dozens of loci associated with late-onset Alzheimer's disease (AD) …